Specifications Table
Product Name – 4-Thioanisolemagnesium bromide, 0.5M solution in THF, AcroSeal®
Quantity/Pack Size – 100ML
Form – Solution
Grade – Research
Application – Organic synthesis, Grignard reactions
Product Overview
4-Thioanisolemagnesium bromide is a specialized 0.5M Grignard reagent dissolved in anhydrous tetrahydrofuran (THF), packaged under the AcroSeal® system to maintain optimal purity and reactivity. This organomagnesium compound is designed for chemists requiring precise control over nucleophilic additions in organic synthesis. The THF solvent enhances solubility while the AcroSeal® packaging prevents moisture contamination, which is critical for maintaining reagent integrity. The solution’s standardized concentration eliminates the need for titration, saving valuable lab time. Its high reactivity makes it particularly suitable for forming carbon-carbon bonds in complex molecular assemblies. The research-grade purity ensures consistent results in sensitive applications where trace impurities could compromise outcomes. The amber glass bottle provides additional protection against light-induced degradation, further preserving the reagent’s stability during storage and handling.
FAQs
1. What precautions should be taken when handling this Grignard reagent?
This reagent is highly moisture-sensitive and pyrophoric. Always handle under inert atmosphere using dry syringes or cannula transfer techniques. Wear appropriate PPE including gloves and safety goggles.
2. How does the AcroSeal® packaging benefit this product?
The AcroSeal® system provides an airtight, moisture-resistant barrier that maintains reagent purity during storage and between uses, reducing the risk of hydrolysis or oxidation.
3. Can this solution be diluted for lower concentration reactions?
While possible, dilution should be performed under strictly anhydrous conditions using freshly distilled THF to prevent premature reagent decomposition.
4. What’s the typical shelf life when stored properly?
When stored unopened at recommended temperatures (2-8°C) and protected from light, the reagent maintains its specified concentration for at least 12 months from date of manufacture.
5. Are there any known incompatibilities with common lab materials?
The reagent reacts violently with water and alcohols. Avoid contact with glassware that hasn’t been properly dried, as even trace moisture can initiate exothermic reactions.