Description
Specifications Table
Product Name – Acetic Acid, Glacial HPLC
Quantity/Pack Size – 1 L
Form – Liquid
Grade – HPLC
Application – Chromatography, solvent preparation, analytical testing
Product Overview
Acetic acid, glacial HPLC grade, is a high-purity solvent designed for demanding laboratory applications where minimal impurities are critical. This ultra-pure variant contains ≤0.05% water content, ensuring consistent performance in high-performance liquid chromatography (HPLC) and other sensitive analytical techniques. The glacial form guarantees a concentrated solution (99.7% minimum purity) without added water, making it ideal for precise solvent preparation, mobile phase adjustments, and sample dilution. Its low UV absorbance and minimal residual contaminants prevent interference in spectroscopic and chromatographic analyses. The acid’s strong acidic properties (pKa ~4.76) also make it effective for pH adjustments in buffers and reaction media. Packaged in high-density polyethylene (HDPE) bottles, it resists chemical degradation and contamination during storage. This grade meets stringent quality standards, including ACS and Reagent specifications, ensuring reliability in quantitative and qualitative laboratory workflows. The product’s stability under standard lab conditions further enhances its utility for long-term use without degradation.
FAQs
1. What is the difference between glacial acetic acid and regular acetic acid?
Glacial acetic acid is the anhydrous (water-free) form with ≥99.7% purity, while regular acetic acid (like vinegar) contains 5-8% acetic acid in water. The glacial form is essential for applications requiring high concentration and minimal water content.
2. Can this HPLC-grade acetic acid be used for sample preparation in mass spectrometry?
Yes, its ultra-low impurity profile and minimal UV absorbance make it suitable for mass spectrometry sample preparation, though compatibility should be verified with specific instrument requirements.
3. What precautions should be taken when handling glacial acetic acid?
Always wear nitrile gloves, safety goggles, and a lab coat. Work in a fume hood due to its pungent vapors and corrosive nature. Avoid contact with skin or eyes, and neutralize spills with sodium bicarbonate.
4. How should this product be stored to maintain its purity?
Store in a tightly sealed original container at room temperature (15–25°C), away from direct sunlight, moisture, and oxidizing agents. Keep the bottle upright to prevent leaks.
5. Is this acetic acid compatible with glassware and plastic lab equipment?
It is compatible with borosilicate glass and HDPE/PP plastics. Avoid prolonged contact with metals or rubber, as it may cause corrosion or degradation over time.
