Specifications Table

Product Name – Acetonitrile, 99.9+%, Extra Dry, AcroSeal® Quantity/Pack Size – 100ML, 1LT, 2.5LT Form – Liquid Grade – HPLC, Extra Dry Application – Chromatography, spectroscopy, sample preparation

Product Overview

Acetonitrile 99.9% Extra Dry is a high-purity solvent designed for demanding laboratory applications where moisture content must be minimized. This HPLC-grade acetonitrile undergoes rigorous purification processes to ensure ultra-low water content (typically <10 ppm), making it ideal for sensitive analytical techniques. The solvent’s exceptional purity reduces baseline noise in chromatography, enhances peak resolution, and prevents column degradation. Packaged in AcroSeal® bottles, it features a tamper-evident seal and a septum cap for controlled dispensing, minimizing contamination risks. The extra-dry formulation is particularly valuable for applications like LC-MS, where trace water can interfere with ionization efficiency. Its low UV cutoff (<190 nm) ensures compatibility with UV-Vis spectroscopy. The solvent is stabilized to prevent peroxide formation, extending shelf life without compromising performance. Whether used as a mobile phase in HPLC or as a solvent for sample dissolution, this acetonitrile delivers consistent, reproducible results. The AcroSeal® packaging also includes a built-in desiccant to maintain dryness during storage and repeated use.

FAQs

1. What is the difference between Extra Dry and regular HPLC-grade acetonitrile?

Extra Dry acetonitrile undergoes additional drying processes to achieve water content below 10 ppm, whereas standard HPLC-grade typically contains 50-100 ppm water. This makes Extra Dry more suitable for moisture-sensitive applications like LC-MS and electrochemical analysis.

2. Can this acetonitrile be used for protein precipitation?

Yes, its high purity and low moisture content make it effective for protein precipitation protocols, though the exact efficiency depends on the sample matrix and protein type.

3. How should I store this solvent to maintain its dryness?

Store the unopened bottle in a cool, dry place away from direct sunlight. After opening, keep the bottle tightly sealed and use the built-in desiccant in the AcroSeal® cap to absorb any ingressed moisture.

4. Is this acetonitrile compatible with PTFE or PVDF syringe filters?

Yes, it is fully compatible with both PTFE and PVDF filters, which are commonly used for sample filtration in HPLC applications.

5. What alternatives exist if I need a less expensive acetonitrile grade?

For less critical applications, ACS-grade acetonitrile (99.5% purity) or spectrophotometric-grade options are available, though they may contain higher moisture and impurity levels.