Description
Specifications Table
| Product Name | Acetonitrile, 99.9%, for HPLC gradient grade, conform Eur.Ph. |
|---|---|
| Pack Size | 1LT, 2.5LT |
| Form | Liquid |
| Grade | HPLC Gradient Grade |
| Application | High-performance liquid chromatography (HPLC), laboratory research, pharmaceutical analysis |
Product Description
When precision matters in your lab work, the quality of your solvents can make all the difference. Acetonitrile, 99.9% for HPLC gradient grade is a high-purity solvent designed specifically for demanding chromatography applications. Whether you’re a student running routine analyses or a researcher developing new methods, this acetonitrile delivers consistent results with minimal interference.
The gradient grade designation means this solvent is optimized for use in HPLC systems where gradient elution is employed. It meets the strict requirements of the European Pharmacopoeia, ensuring it’s free from impurities that could affect your chromatographic separations or compromise your data integrity. This makes it particularly valuable in pharmaceutical analysis, environmental testing, and other applications where regulatory compliance is critical.
One of the key advantages of this acetonitrile is its exceptional UV transparency. In HPLC applications where UV detection is used, this property helps prevent false peaks or baseline drift that could occur with lower-grade solvents. The 99.9% purity level also means you’ll experience fewer column contamination issues, extending the life of your expensive HPLC columns.
For researchers working on method development, this solvent provides the reliability needed to establish robust analytical procedures. Students will appreciate how it helps achieve clean chromatograms in their lab experiments. And for quality control laboratories, it offers the consistency required for reproducible results in routine testing.
Upgrade your chromatography workflow with high-purity acetonitrile. Order your HPLC-grade solvent today and experience the difference quality makes in your analyses.
At eqipped, we understand that lab supplies are more than just products – they’re tools that enable discovery. That’s why we’ve carefully selected this acetonitrile to meet the exacting standards of modern laboratories. Whether you’re setting up a new lab or restocking your supplies, you can trust this solvent to perform when it matters most.
Key Applications
This HPLC-grade acetonitrile finds use in numerous laboratory applications. In pharmaceutical analysis, it’s commonly used for drug purity testing and impurity profiling. Environmental labs rely on it for pesticide residue analysis and water quality testing. Food safety laboratories use it in methods for detecting contaminants or additives. Academic research labs find it invaluable for protein analysis and other biochemical applications.
The solvent’s low viscosity also makes it particularly suitable for UHPLC (Ultra High Performance Liquid Chromatography) systems where high pressure is required. Its miscibility with water allows for flexible mobile phase preparation in reversed-phase chromatography, which is the most common HPLC mode used today.
Safety and Handling
While acetonitrile is a valuable laboratory solvent, it requires proper handling. Always use in a well-ventilated area or under a fume hood. Wear appropriate personal protective equipment including nitrile gloves and safety goggles. The solvent is flammable, so keep it away from heat sources and open flames. Store in a cool, dry place with the container tightly sealed when not in use.
For disposal, follow your institution’s chemical waste procedures. Never pour acetonitrile down the drain or dispose of it with regular waste. Many laboratories collect organic solvent waste in properly labeled containers for professional disposal.
Why This Grade Matters
Not all acetonitrile is created equal. The gradient grade specification is particularly important for modern HPLC systems. Lower-grade solvents may contain UV-absorbing impurities that can interfere with detection, or residual acids that can affect pH-sensitive separations. This high-purity grade eliminates these concerns, giving you confidence in your results.
The European Pharmacopoeia conformity adds another layer of assurance. This means the solvent has been tested against strict standards for identity, purity, and other quality attributes. For laboratories working under GLP or GMP guidelines, this documentation can be crucial for audit purposes.
Storage Recommendations
To maintain the high purity of this acetonitrile, proper storage is essential. Keep the container tightly sealed when not in use to prevent moisture absorption. Store at room temperature, away from direct sunlight. For laboratories in humid climates, consider using a desiccant in the storage area to maintain optimal conditions.
If you notice any discoloration or particulate matter in the solvent, do not use it as this may indicate contamination. The shelf life is typically long when stored properly, but always check the expiration date on the container.
FAQs
What makes HPLC gradient grade acetonitrile different from regular acetonitrile?
HPLC gradient grade acetonitrile undergoes additional purification steps to remove UV-absorbing impurities and other contaminants that could interfere with chromatographic separations. It’s specifically tested for use in gradient elution methods where solvent composition changes during the run.
Can I use this acetonitrile for LC-MS applications?
While this grade is excellent for HPLC with UV detection, LC-MS applications typically require even higher purity solvents with ultra-low levels of ionic contaminants. For mass spectrometry, you might want to consider LC-MS grade acetonitrile for optimal performance.
What’s the typical shelf life of this product?
When stored properly in its original container at room temperature, this acetonitrile typically has a shelf life of 2-3 years. Always check the expiration date on the bottle and inspect the solvent for any signs of contamination before use.
Is this acetonitrile suitable for DNA/RNA extraction?
While acetonitrile is sometimes used in nucleic acid precipitation protocols, this particular grade is optimized for chromatography rather than molecular biology applications. For DNA/RNA work, you might want to consider molecular biology grade solvents.
How should I dispose of unused acetonitrile?
Acetonitrile should be disposed of as hazardous waste according to your local regulations. Collect in a properly labeled waste container and arrange for disposal through your institution’s environmental health and safety department.
