Description
Specifications Table
Product Name – Acetonitrile HPLC Grade
Quantity/Pack Size – 4 L
Form – Liquid
Grade – HPLC
Application – Chromatography, sample preparation, solvent extraction
Product Overview
Acetonitrile HPLC Grade is a high-purity, low-viscosity solvent designed for demanding chromatographic applications where consistency and minimal interference are critical. With a water content of ≤0.01% and exceptionally low UV absorbance (≤0.05 AU at 200 nm), this reagent-grade acetonitrile ensures baseline stability and peak resolution in HPLC, LC-MS, and UV-Vis spectroscopy. Its high solvent strength (polarity index 5.8) makes it ideal for dissolving polar and nonpolar compounds, while its low reactivity preserves sample integrity. The solvent undergoes rigorous distillation and filtration to remove trace impurities, particulate matter, and ionic contaminants, meeting or exceeding ACS and USP standards. Packaged in amber glass bottles to prevent photodegradation, it maintains stability for up to 24 months when stored under nitrogen at 15–25°C. Compatible with most stationary phases, including C18 and silica-based columns, this acetonitrile variant minimizes column degradation and extends hardware lifespan. Its low acidity (≤0.002 meq/g) and peroxide-free formulation reduce artifact formation in sensitive analyses, making it a reliable choice for quantitative and qualitative laboratory workflows.
FAQs
1. What is the maximum UV absorbance for this acetonitrile at 200 nm?
This HPLC-grade acetonitrile has a maximum UV absorbance of ≤0.05 AU at 200 nm, ensuring minimal interference in low-wavelength detection.
2. Can this solvent be used with stainless steel HPLC systems?
Yes, it is fully compatible with stainless steel components and does not cause corrosion or leaching when used within standard operating parameters.
3. How does the water content compare to ACS-grade acetonitrile?
The water content in this HPLC-grade variant is strictly controlled at ≤0.01%, which is significantly lower than typical ACS-grade acetonitrile (≤0.2%).
4. What precautions should be taken during storage to maintain purity?
Store the bottle tightly sealed under nitrogen in a cool, dark place (15–25°C) to prevent moisture absorption and photodegradation. Avoid repeated opening to minimize oxygen exposure.
5. Is this acetonitrile suitable for gradient elution in LC-MS?
Yes, its low particulate count (<1 particle/mL ≥0.5 µm) and consistent volatility make it ideal for gradient elution in LC-MS applications without baseline drift.
