Description
Specifications Table
Product Name – Acetonitrile USP
Quantity/Pack Size – 100 ml | 250 ml | 500 ml | 1 L | 2.5 L | 4 L
Form – Liquid (Clear, Colorless)
Grade – USP/HPLC/ACS
Application – HPLC mobile phase, LC-MS, solvent extraction, protein sequencing, DNA synthesis
Product Overview
Acetonitrile USP from eqipped is a high-purity, anhydrous solvent designed for critical laboratory applications where consistency and minimal interference are paramount. Distilled under strict quality controls, this grade meets USP, ACS, and HPLC standards, ensuring ≤0.005% water content and ultra-low UV absorbance (<190 nm), which prevents baseline drift in chromatographic analyses. The solvent undergoes rigorous filtration (0.22 µm) to eliminate particulate contamination, making it suitable for sensitive instrumentation like UHPLC and mass spectrometry. Its low viscosity (0.34 cP at 25°C) and high dielectric constant (37.5) enable efficient dissolution of polar and nonpolar compounds, while the absence of stabilizers or additives guarantees reproducible results across batches. Packaged in amber glass bottles with PTFE-lined caps, it resists moisture ingress and photodegradation, preserving integrity during storage. Compatible with most organic solvents and aqueous buffers, it serves as a universal diluent for sample preparation, though users should verify miscibility for specific protocols. For long-term storage, maintain unopened bottles at 15–25°C, away from ignition sources, as acetonitrile is highly flammable (flash point: 6°C). Always handle in a fume hood with proper PPE to mitigate inhalation and skin contact risks.
FAQs
1. Can this Acetonitrile USP be used directly in LC-MS without further purification?
Yes, this grade is pre-filtered and tested for LC-MS compatibility, with residual impurities (e.g., acetone, acrylonitrile) below 10 ppm. However, for ultra-trace analysis, additional filtration or degassing may be recommended based on your instrument’s sensitivity.
2. What is the typical shelf life of unopened Acetonitrile USP bottles?
When stored under ideal conditions (sealed, 15–25°C, away from light), the shelf life is 24 months from the date of manufacture. Opened bottles should be used within 6 months or reprocessed if contamination is suspected.
3. Is this acetonitrile compatible with plastic labware like polypropylene or HDPE?
Acetonitrile can degrade certain plastics over time. For short-term storage (<24 hours), HDPE is acceptable, but glass or PTFE-coated containers are preferred for long-term contact to avoid leaching or container failure.
4. How does this compare to HPLC-grade acetonitrile from other brands?
This product matches or exceeds industry benchmarks for UV transparency (≤0.05 AU at 190 nm) and water content. Independent batch testing confirms lower aldehyde/ketone impurities than many competitors, reducing ghost peaks in gradient separations.
5. What safety precautions are essential when handling large volumes (e.g., 4 L bottles)?h4>
For bulk handling, use a spill-containment tray and ground the container to prevent static discharge. Transfer in a fume hood with a dedicated acetonitrile-resistant pump, and avoid metal tools (use PTFE or glass) to prevent spark risks. Always have a Class B fire extinguisher nearby.
