Description
Specifications Table
| Product Name | Acetonitrile with 0.1% Acetic Acid for LCMS |
|---|---|
| Pack Size | 1L |
| Form | Liquid |
| Grade | LC-MS Grade |
| Application | Liquid Chromatography-Mass Spectrometry (LC-MS), HPLC, analytical research |
Product Description
When precision matters in liquid chromatography-mass spectrometry (LC-MS), the quality of your solvent can make or break your results. Acetonitrile with 0.1% acetic acid from eqipped is specifically formulated to meet the stringent demands of LC-MS applications, ensuring minimal background noise and maximum sensitivity for your analyses.
This high-purity solvent is designed to enhance peak resolution and reproducibility, making it a trusted choice for researchers, pharmacologists, and analytical chemists. Whether you’re working in pharmaceutical development, environmental testing, or clinical diagnostics, this acetonitrile blend delivers consistent performance, reducing the risk of ion suppression and improving detection limits.
The addition of 0.1% acetic acid stabilizes the pH, which is crucial for maintaining the integrity of sensitive compounds during separation. This makes it particularly useful for analyzing polar and acidic analytes, where pH control is essential for accurate quantification.
At eqipped, we understand that reliability in lab supplies is non-negotiable. That’s why we source this acetonitrile blend from CDH, a brand synonymous with quality and consistency in analytical reagents. Every batch undergoes rigorous quality checks to ensure it meets LC-MS grade specifications, so you can focus on your research without worrying about solvent-related inconsistencies.
Upgrade your LC-MS workflow with acetonitrile that’s built for accuracy. Buy Acetonitrile with 0.1% Acetic Acid online today and experience the difference in your results.
Why This Solvent Stands Out for LC-MS
Not all acetonitrile is created equal, especially when it comes to mass spectrometry. Here’s what sets this product apart:
The ultra-low impurity profile minimizes background interference, which is critical when working with trace-level analytes. Many standard-grade solvents contain residual contaminants that can mask your target compounds or cause false positives. With this LC-MS grade acetonitrile, you get a cleaner baseline, allowing for more confident data interpretation.
The 0.1% acetic acid modifier is pre-mixed to the optimal concentration, saving you time and reducing the risk of human error in manual preparation. This is particularly beneficial for high-throughput labs where consistency across samples is paramount. The acidified solvent also helps in improving the ionization efficiency of certain compounds, leading to better signal intensity in your mass spectrometer.
Compatibility is another key advantage. This solvent works seamlessly with most LC-MS systems, including those using electrospray ionization (ESI) sources. It’s also suitable for reverse-phase HPLC applications, making it a versatile addition to your lab’s solvent inventory.
For students and educators, this solvent serves as an excellent teaching tool. It allows you to demonstrate the importance of solvent purity in analytical chemistry, showing how the right choice of reagents can significantly impact experimental outcomes. The consistent performance also makes it ideal for training new researchers on LC-MS techniques.
Applications in Research and Industry
This acetonitrile blend finds applications across a wide range of scientific disciplines:
In pharmaceutical research, it’s used for drug metabolism studies, impurity profiling, and bioanalysis of drugs in biological matrices. The high purity ensures that even low-level metabolites can be detected without interference from solvent impurities.
Environmental scientists rely on it for the analysis of pesticides, herbicides, and other contaminants in water and soil samples. The acidified solvent helps in the efficient extraction and separation of these compounds, leading to more accurate environmental assessments.
Clinical laboratories use it for diagnostic testing, including the quantification of biomarkers and therapeutic drug monitoring. The reproducibility of this solvent is crucial in clinical settings where results directly impact patient care decisions.
Food safety labs employ it for the detection of residues and additives in food products. The solvent’s compatibility with various sample preparation techniques makes it a go-to choice for complex food matrices.
For academic institutions, this solvent is invaluable in teaching advanced analytical techniques. It allows students to experience firsthand how solvent quality affects chromatographic separation and mass spectral data.
Handling and Storage Recommendations
To maintain the integrity of this high-purity solvent, proper handling and storage are essential. Always store the bottle tightly sealed in a cool, dry place, away from direct sunlight and sources of ignition. Acetonitrile is flammable, so keep it away from open flames and sparks.
When transferring the solvent, use clean, dedicated glassware to avoid contamination. It’s also advisable to work in a well-ventilated area or under a fume hood, as acetonitrile vapors can be harmful if inhaled.
For long-term storage, consider using an inert gas blanket to minimize oxidation and moisture absorption. This is particularly important if you’re using the solvent intermittently over an extended period.
Always refer to the Safety Data Sheet (SDS) for comprehensive handling and disposal guidelines. Proper disposal of solvent waste is crucial to ensure environmental safety and compliance with local regulations.
Risk Note
Warning: Acetonitrile is a flammable liquid and vapor. It may be harmful if inhaled, swallowed, or absorbed through the skin. Causes eye and skin irritation. May cause damage to organs through prolonged or repeated exposure. Use only in a well-ventilated area with appropriate personal protective equipment (PPE). Keep away from heat, sparks, and open flames. In case of contact, rinse immediately with plenty of water and seek medical advice. Store in a tightly closed container in a cool, dry place. Dispose of in accordance with local regulations.
FAQs
What makes this acetonitrile suitable for LC-MS applications?
This acetonitrile is specifically purified to remove impurities that can interfere with mass spectrometry detection. The addition of 0.1% acetic acid helps stabilize the pH, reducing ion suppression and improving signal intensity for better analytical results.
Can I use this solvent for HPLC as well?
Yes, this LC-MS grade acetonitrile is also suitable for HPLC applications. Its high purity makes it ideal for both techniques, ensuring consistent performance across different analytical methods.
How should I store this solvent to maintain its quality?
Store the bottle tightly sealed in a cool, dry place away from direct sunlight and ignition sources. For extended storage, consider using an inert gas blanket to prevent oxidation and moisture absorption.
Is this solvent compatible with all LC-MS systems?
This acetonitrile blend is compatible with most LC-MS systems, particularly those using electrospray ionization (ESI) sources. However, always check your instrument’s specifications for any specific solvent requirements.
What safety precautions should I take when handling this solvent?
Always wear appropriate PPE, including gloves and safety goggles, when handling acetonitrile. Work in a well-ventilated area or under a fume hood, and avoid inhalation or skin contact. Follow all local safety and disposal regulations.
