Description
Specifications Table
| Product Name | Boc-Glu(Obzl)-Oh (Cryst) |
|---|---|
| Pack Size | 25 G |
| Form | Crystalline |
| Grade | Research Grade |
| Application | Peptide synthesis, biochemical research |
Product Description
Boc-Glu(Obzl)-Oh (Cryst) is a high-quality protected glutamate derivative widely used in peptide synthesis and biochemical research. This crystalline compound features a tert-butoxycarbonyl (Boc) protecting group on the amino terminus and a benzyl ester (Obzl) on the carboxyl group, making it ideal for solid-phase peptide synthesis (SPPS). Researchers and students working in organic chemistry, pharmacology, or molecular biology will find this reagent essential for synthesizing custom peptides with precision.
The benzyl ester protection allows for selective deprotection under mild conditions, ensuring compatibility with various synthesis protocols. Whether you’re developing therapeutic peptides, studying enzyme-substrate interactions, or conducting structural biology research, this compound delivers consistent results. eqipped offers this Merck product in a convenient 25g pack size, ensuring you have the right quantity for your lab experiments without excess waste.
When you buy Boc-Glu(Obzl)-Oh (Cryst) online from eqipped, you’re choosing a trusted supplier committed to providing authentic, high-purity chemicals for Indian researchers. Our streamlined ordering process and reliable logistics ensure your research materials arrive promptly, so you can focus on your work without delays.
Key Applications in Research
This versatile compound finds applications in multiple research areas:
Peptide synthesis remains its primary use, where the Boc protecting group allows for controlled amino acid chain elongation. The benzyl ester protection on the side chain carboxyl group prevents unwanted reactions during synthesis, enabling the creation of complex peptide sequences with high yield and purity.
In medicinal chemistry, researchers use Boc-Glu(Obzl)-Oh (Cryst) to develop peptide-based drugs and study structure-activity relationships. The compound’s stability and predictable behavior make it valuable for creating analogs of naturally occurring peptides with enhanced therapeutic properties.
Biochemical studies benefit from this reagent when investigating enzyme mechanisms or protein interactions. The protected glutamate derivative helps create substrates that mimic natural biological molecules while allowing researchers to control reaction conditions precisely.
For students learning organic synthesis techniques, this compound serves as an excellent model for understanding protecting group chemistry and solid-phase synthesis methods. Its well-documented behavior makes it a reliable choice for educational laboratories.
Handling and Storage Recommendations
To maintain the integrity of your Boc-Glu(Obzl)-Oh (Cryst), store it in a cool, dry place away from direct sunlight. The compound should be kept in its original container with the lid tightly sealed to prevent moisture absorption, which could compromise its effectiveness in synthesis reactions.
When handling this chemical, always use appropriate personal protective equipment including gloves and safety goggles. Work in a well-ventilated area or under a fume hood when performing synthesis reactions to minimize exposure to potential fumes.
For long-term storage, consider keeping the container in a desiccator to maintain optimal conditions. This is particularly important in humid climates where moisture can more easily affect sensitive chemicals.
Why This Compound Matters in Modern Research
The development of protected amino acid derivatives like Boc-Glu(Obzl)-Oh (Cryst) revolutionized peptide synthesis by enabling the creation of complex molecules that were previously difficult to produce. This compound specifically addresses the challenge of glutamate’s side chain carboxyl group, which would otherwise interfere with synthesis reactions.
Modern research laboratories rely on such high-purity reagents to achieve reproducible results in their experiments. Whether you’re working on drug discovery, protein engineering, or fundamental biochemical studies, having access to reliable protected amino acids is crucial for success.
eqipped understands the importance of quality reagents in scientific research. That’s why we source our chemicals from reputable manufacturers like Merck and maintain strict quality control measures to ensure you receive products that meet the highest standards.
FAQs
What is the purity level of Boc-Glu(Obzl)-Oh (Cryst) from Merck?
This product meets Merck’s high purity standards, typically exceeding 98% purity as determined by HPLC analysis. The crystalline form ensures consistent quality for research applications.
Can I use this compound for Fmoc-based peptide synthesis?
While Boc-Glu(Obzl)-Oh (Cryst) is designed for Boc chemistry, you can incorporate it into Fmoc strategies by first removing the Boc group and then reprotecting with Fmoc if needed for your specific synthesis protocol.
What solvents are recommended for dissolving this compound?
The compound typically dissolves well in organic solvents like dimethylformamide (DMF), dichloromethane (DCM), or N-methyl-2-pyrrolidone (NMP). Always check your specific synthesis protocol for solvent recommendations.
Is this product suitable for undergraduate chemistry labs?
Yes, this compound is appropriate for educational settings where students are learning peptide synthesis techniques. Its predictable behavior makes it a good teaching tool for organic chemistry practicals.
How quickly can I receive my order from eqipped?
Delivery times vary by location, but most orders ship within 1-2 business days. Major Indian cities typically receive their orders within 3-5 business days, while remote areas may take slightly longer.
Risk Note
Boc-Glu(Obzl)-Oh (Cryst) is for research use only and not for human consumption. Handle with care as it may cause skin and eye irritation. Use appropriate personal protective equipment and work in a well-ventilated area. In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Store away from incompatible materials and heat sources.
