Description
Specifications Table
Product Name – Butanesulfonic acid, sodium salt, 99+%, HPLC grade
Quantity/Pack Size – 5GR, 25GR
Form – Solid (powder/crystalline)
Grade – HPLC (High-Performance Liquid Chromatography)
Application – Chromatography, ion-pairing reagent, analytical standards
Product Overview
Butanesulfonic acid, sodium salt (99%+ purity, HPLC grade) is a high-quality ion-pairing reagent widely used in chromatographic separations and analytical chemistry. Its molecular structure ensures strong hydrophobic interactions, making it ideal for reverse-phase HPLC applications where precise retention control is required. The sodium salt form enhances solubility in aqueous mobile phases, improving peak symmetry and resolution for complex mixtures. This grade is rigorously tested to meet strict purity standards, minimizing baseline noise and ensuring reproducible results. The compound’s low UV absorbance at common detection wavelengths (210–254 nm) prevents interference with analyte signals. Its stability under typical HPLC conditions (pH 2–8) allows for long-term storage without degradation. The fine, free-flowing powder dissolves rapidly in polar solvents, facilitating easy preparation of mobile phases. Compatible with most HPLC columns, including C18 and phenyl-hexyl stationary phases, it serves as a reliable alternative to trifluoroacetic acid (TFA) for basic compound separations. The 5GR and 25GR pack sizes provide flexibility for both small-scale research and bulk applications.
FAQs
1. What is the solubility of sodium butanesulfonate in water?
It is highly soluble in water (over 500 g/L at 20°C), forming clear, colorless solutions suitable for HPLC mobile phases.
2. Can this be used with mass spectrometry (LC-MS) applications?
Yes, but caution is advised due to potential ion suppression effects; lower concentrations (≤10 mM) are recommended for LC-MS compatibility.
3. How does this compare to heptanesulfonic acid as an ion-pairing reagent?
Sodium butanesulfonate offers shorter retention times for basic compounds and is less hydrophobic, making it better for rapid separations.
4. What is the recommended storage temperature?
Store at room temperature (15–25°C) in a tightly sealed container to prevent moisture absorption and degradation.
5. Is this product compatible with gradient HPLC methods?
Yes, it remains stable during gradient elution and does not precipitate when mixed with organic modifiers like acetonitrile or methanol.
