Description
Specifications Table
Product Name – Butanesulfonic acid, sodium salt BAKER™
Quantity/Pack Size – 25 g
Form – Solid (powder/crystals)
Grade – ACS reagent
Application – Ion-pair chromatography, buffer preparation, protein solubilization
Product Overview
Butanesulfonic acid, sodium salt (BAKER™) is a high-purity, ACS-grade reagent designed for precision applications in analytical and biochemical laboratories. This sodium butanesulfonate variant is widely recognized for its role as an ion-pairing agent in reversed-phase HPLC, where it enhances retention and separation of polar compounds. Its strong anionic properties make it ideal for buffer systems requiring stable pH control, particularly in protein and peptide analysis. The compound’s high solubility in water and organic solvents ensures compatibility with diverse experimental protocols. With a purity of ≥99%, this BAKER™-grade reagent minimizes interference in sensitive assays, ensuring reliable and reproducible results. The solid form (powder or crystals) allows for easy handling and accurate weighing, while its low moisture content prevents clumping during storage. Whether used in chromatographic separations or as a stabilizing agent in biochemical reactions, this sodium butanesulfonate delivers consistent performance for demanding laboratory workflows.
FAQs
1. What is the primary use of sodium butanesulfonate in chromatography?
It acts as an ion-pairing reagent in reversed-phase HPLC to improve retention and separation of ionic or polar analytes by forming neutral ion pairs.
2. Can this compound be used in mass spectrometry?
Yes, but it requires careful optimization due to potential ion suppression effects. Lower concentrations are recommended to minimize interference.
3. How should this product be stored to maintain stability?
Store in a tightly sealed container at room temperature, protected from moisture and light. Avoid prolonged exposure to air to prevent hydration.
4. Is this sodium butanesulfonate compatible with aqueous and organic mobile phases?
Yes, it is soluble in both water and common organic solvents like methanol and acetonitrile, making it versatile for mixed-phase chromatography.
5. What alternatives exist for ion-pairing in HPLC if this product is unavailable?
Alternatives include heptanesulfonic acid sodium salt, octanesulfonic acid sodium salt, or trifluoroacetic acid, depending on the analyte’s properties and separation requirements.
