Description
Specifications Table
Product Name – Ethyl acetate, anhydrous, 50 ppm H2O
Quantity/Pack Size – 250 ml
Form – Liquid
Grade – ACS reagent, 99.5%
Application – Solvent extraction, chromatography, organic synthesis
Product Overview
This anhydrous ethyl acetate is meticulously purified to contain ≤50 ppm residual water, making it ideal for applications where trace moisture can compromise results. Distilled under inert conditions and stabilized with molecular sieves, it maintains its ultra-low water content throughout storage when handled properly. The ACS reagent grade ensures ≥99.5% purity with tightly controlled impurities, while the absence of added stabilizers prevents interference in analytical applications. Its low UV absorbance (≤0.05 at 254nm) and minimal residual acids/aldehydes make it particularly suitable for HPLC and spectrophotometric work. The solvent’s 0.22μm filtration eliminates particulate contamination, while its sealed packaging with PTFE-lined caps prevents atmospheric moisture ingress. Compared to standard ethyl acetate, this anhydrous grade offers significantly improved reaction yields in moisture-sensitive processes like Grignard reactions or silylation chemistry. The product’s consistent lot-to-lot performance is verified through GC and Karl Fischer titration analysis, with certificates of analysis provided for each batch.
FAQs
1. How does the 50 ppm water specification compare to standard ethyl acetate grades?
Standard reagent-grade ethyl acetate typically contains 100-300 ppm water, while technical grades may exceed 500 ppm. This anhydrous grade’s ≤50 ppm specification represents a 4-10x reduction in moisture content, critical for reactions where water acts as a competing nucleophile or causes catalyst deactivation. The purification process involves azeotropic distillation followed by molecular sieve treatment to achieve this ultra-low moisture level.
2. What precautions should be taken when transferring this solvent to maintain anhydrous conditions?
Always use oven-dried glassware and store the bottle under nitrogen when not in use. Transfer using a dry syringe or cannula through a septum to minimize air exposure. Avoid pouring directly from the bottle as this introduces moisture. For critical applications, further dry the solvent over activated 3Å molecular sieves immediately before use, though this is typically unnecessary given the product’s tight moisture specification.
3. Can this be used as a direct replacement for standard ethyl acetate in existing protocols?
Yes, but you may observe improved yields or cleaner reactions due to the reduced water content. Some protocols specifically call for anhydrous solvent – in these cases, this product meets those requirements without additional drying. For non-critical applications where moisture isn’t a concern, the higher purity may still benefit your results through reduced side reactions.
4. What’s the typical shelf life when stored properly?
When kept tightly sealed in its original container at 15-25°C, the product maintains its ≤50 ppm water specification for at least 12 months from the date of manufacture. The PTFE-lined cap and nitrogen headspace in the bottle minimize moisture ingress. After opening, use within 6 months or verify moisture content via Karl Fischer titration before critical applications.
5. How does the packaging prevent moisture absorption during storage?
The amber glass bottle features a PTFE-faced septum cap that creates an airtight seal. The headspace is flushed with nitrogen during packaging to displace oxygen and moisture. For additional protection during shipping, each bottle is sealed in a moisture-barrier bag with desiccant. This multi-layer protection system maintains the anhydrous specification even in humid Indian climates during transit.
