Description
Specifications Table
Product Name – Ethyl trifluoroacetate
Quantity/Pack Size – 100 g
Form – Liquid
Grade – 99% Pure
Application – Organic synthesis, fluorination, intermediate reactions
Product Overview
Ethyl trifluoroacetate is a high-purity, colorless liquid reagent widely used in organic synthesis due to its strong electrophilic properties. With a purity of 99%, it serves as a key intermediate in fluorination reactions, enabling the introduction of trifluoromethyl groups into organic compounds. Its sharp, pungent odor is characteristic of volatile esters, and it is highly soluble in organic solvents like ethanol, ether, and chloroform. The compound is moisture-sensitive, requiring storage under inert conditions to prevent hydrolysis. Its low boiling point (60-62°C) makes it suitable for distillation and purification processes. Ethyl trifluoroacetate is compatible with standard glassware but should be handled in a fume hood due to its irritant nature. The reagent’s stability under refrigeration ensures a long shelf life when stored properly in airtight containers. Its molecular formula (C4H5F3O2) and molar mass (142.08 g/mol) make it a versatile building block for synthesizing pharmaceuticals, agrochemicals, and specialty materials. Always verify compatibility with other reagents before use to avoid unintended side reactions.
FAQs
1. What is the primary application of ethyl trifluoroacetate in lab settings?
It is primarily used as a fluorinating agent in organic synthesis, particularly for introducing trifluoromethyl groups into molecules.
2. Can ethyl trifluoroacetate be stored at room temperature?
While short-term storage at room temperature is possible, long-term storage under refrigeration (2-8°C) is recommended to maintain stability.
3. What safety precautions should be taken while handling this compound?
Use in a well-ventilated fume hood, wear nitrile gloves, and avoid inhalation or skin contact due to its irritant properties.
4. Is this reagent compatible with aqueous solutions?
No, it hydrolyzes in the presence of water, so it should be stored under anhydrous conditions.
5. What alternatives exist for trifluoromethylation reactions?
Alternatives include trifluoroacetic anhydride or trifluoromethyl iodide, though reactivity and selectivity may vary.
