Description
Specifications Table
Product Name – Ethylmagnesium chloride, 2.7M (25 wt.%) solution in THF, AcroSeal® Quantity/Pack Size – 100ML, 800ML Form – Liquid (THF solution) Grade – Reagent grade Application – Grignard reagent for organic synthesis
Product Overview
Ethylmagnesium chloride 2.7M solution in tetrahydrofuran (THF) is a highly reactive Grignard reagent supplied in air-tight AcroSeal® packaging to prevent moisture contamination. This reagent-grade solution contains 25 wt.% ethylmagnesium chloride dissolved in ultra-dry THF, ensuring consistent performance in carbon-carbon bond formation, nucleophilic additions, and other organometallic reactions. The standardized 2.7M concentration provides precise stoichiometric control, while the AcroSeal® technology maintains reagent integrity during storage and handling. The solution is stabilized with trace amounts of inhibitors to minimize decomposition, making it ideal for demanding synthetic applications. As a moisture-sensitive compound, it requires inert atmosphere handling and is compatible with standard Schlenk techniques. The THF solvent is purified to remove peroxides and water, enhancing reagent stability. This formulation is particularly valued for its high yield potential in complex organic transformations where ethyl group transfer is required.
FAQs
1. What is the shelf life of Ethylmagnesium chloride 2.7M in THF?
The unopened AcroSeal® bottle maintains stability for 12 months when stored at 2-8°C under nitrogen. Once opened, use within 3 months.
2. Can this reagent be used with other solvents besides THF?
While formulated in THF, it can be diluted with anhydrous diethyl ether or toluene, though reactivity may vary. Avoid protic solvents.
3. How should I dispose of unused Ethylmagnesium chloride solution?
Neutralize with isopropanol or dilute acetic acid before disposal. Follow local hazardous waste regulations for organometallic compounds.
4. What’s the difference between 2.0M and 2.7M concentrations?
The 2.7M solution offers higher reagent density per volume, reducing solvent waste in large-scale reactions while maintaining equivalent reactivity.
5. Is this compatible with glass syringes for transfer?
Yes, but use PTFE-tipped needles and purge with nitrogen to prevent moisture exposure during transfer operations.
