Description
Specifications Table
| Product Name | Fmoc-Asp(Otbu)-Thr(Psime,Mepro)-Oh |
|---|---|
| Pack Size | 100 G |
| Form | Solid |
| Grade | Research Grade |
| Application | Peptide Synthesis |
Product Description
Fmoc-Asp(Otbu)-Thr(Psime,Mepro)-Oh is a specialized amino acid derivative designed for high-efficiency peptide synthesis. This Merck-certified reagent features an Fmoc-protected aspartic acid with tert-butyl ester protection and a pseudoproline dipeptide unit, ensuring minimal side reactions during synthesis.
Researchers and students working on complex peptide sequences will appreciate its stability and compatibility with standard Fmoc chemistry protocols. The compound’s unique structure helps prevent aggregation and improves solubility, making it ideal for challenging synthesis projects.
When you buy Fmoc-Asp(Otbu)-Thr(Psime,Mepro)-Oh from eqipped, you’re getting a product that meets strict quality standards. Each batch undergoes rigorous testing to confirm purity and functionality, giving you confidence in your experimental results.
Key Applications
This reagent is particularly valuable for:
- Synthesizing difficult peptide sequences with high yield
- Reducing secondary structure formation during synthesis
- Improving coupling efficiency in solid-phase peptide synthesis
- Research applications requiring precise amino acid incorporation
For researchers seeking reliable peptide synthesis reagents, Fmoc-Asp(Otbu)-Thr(Psime,Mepro)-Oh offers exceptional performance and consistency.
Handling and Storage
Store this compound at -20°C in a dry, inert atmosphere. Avoid exposure to moisture and light. For best results, use within 12 months of purchase. Always follow standard laboratory safety protocols when handling chemical reagents.
Why This Product Stands Out
Unlike standard amino acid derivatives, this compound incorporates a pseudoproline unit that significantly enhances synthesis efficiency. The combination of Fmoc protection and tert-butyl ester groups provides optimal stability during the synthesis process while allowing for clean deprotection when needed.
Students and researchers will find this reagent particularly useful for projects involving complex peptides where traditional methods might fail. Its specialized structure helps overcome common synthesis challenges, making it a valuable addition to any peptide chemistry toolkit.
FAQs
What is the purity level of this Fmoc-Asp(Otbu)-Thr(Psime,Mepro)-Oh?
This product meets Merck’s high purity standards, typically >95% as confirmed by HPLC analysis.
Can this be used with standard Fmoc deprotection protocols?
Yes, it’s fully compatible with standard Fmoc chemistry using piperidine in DMF for deprotection.
What’s the typical coupling time for this reagent?
Most researchers find 30-60 minutes sufficient for complete coupling, though this may vary based on your specific synthesis conditions.
Is this suitable for automated peptide synthesizers?
Absolutely. This reagent works well with both manual and automated synthesis systems.
How should I store opened containers?
After opening, seal tightly and store under nitrogen at -20°C to maintain stability.
