Description
Specifications Table
| Product Name | Fmoc-Cys(Trt)-Opfp 5 G | 8.52126.0005 | Merck |
|---|---|
| Quantity/Pack Size | 5 G |
| Form | Solid |
| Grade | Research Grade |
| Application | Peptide Synthesis, Biochemical Research |
Product Description
Fmoc-Cys(Trt)-Opfp is a high-quality amino acid derivative widely used in solid-phase peptide synthesis (SPPS). The Fmoc (9-fluorenylmethoxycarbonyl) protecting group ensures efficient coupling, while the trityl (Trt) protection on cysteine prevents unwanted side reactions. This compound is essential for researchers and labs working on peptide-based therapeutics, protein studies, or biochemical assays.
Whether you’re synthesizing custom peptides or conducting advanced research, this reagent offers reliability and consistency. The pentafluorophenyl (OPfp) ester enhances reactivity, making it a preferred choice for demanding synthesis protocols.
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Why This Product Stands Out
Peptide synthesis requires precision, and the quality of your reagents directly impacts results. Fmoc-Cys(Trt)-Opfp from Merck is manufactured under strict quality controls, ensuring high purity and batch-to-batch consistency. The trityl protection is particularly valuable as it prevents cysteine oxidation and side-chain reactions during synthesis.
Researchers in academia and industry rely on this compound for projects ranging from drug discovery to structural biology. Its compatibility with standard Fmoc chemistry protocols makes it a versatile tool in any lab.
Applications in Research
This product is commonly used in:
- Solid-phase peptide synthesis (SPPS)
- Protein engineering and modification
- Bioconjugation studies
- Development of cysteine-rich peptides
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Handling and Storage
Store Fmoc-Cys(Trt)-Opfp in a cool, dry place, away from direct sunlight. Keep the container tightly sealed to prevent moisture absorption. For long-term storage, consider desiccants or inert gas purging to maintain stability.
Always handle this compound in a well-ventilated fume hood, using appropriate personal protective equipment (PPE) such as gloves and safety goggles.
FAQs
What is the shelf life of Fmoc-Cys(Trt)-Opfp?
When stored properly, this product has a shelf life of 12–24 months. Check the certificate of analysis for batch-specific details.
Can this be used in automated peptide synthesizers?
Yes, Fmoc-Cys(Trt)-Opfp is compatible with most automated SPPS systems. Ensure proper dissolution in DMF or other suitable solvents before use.
Is this product suitable for therapeutic peptide synthesis?
While it meets research-grade standards, additional validation may be required for clinical applications. Consult regulatory guidelines for GMP compliance.
What solvents work best for dissolving this compound?
DMF (dimethylformamide) is the most common solvent, but DMSO or NMP can also be used depending on your protocol.
Does eqipped offer discounts for bulk orders?
Yes, we provide competitive pricing for bulk purchases. Reach out to our team for a customized quote.





