Description
Specifications Table
| Product Name | Fmoc-D-Asp-Otbu 1 G | 8.52144.0001 | Merck |
|---|---|
| Quantity/Pack Size | 1 G |
| Form | Solid |
| Grade | Research Grade |
| Application | Peptide Synthesis |
Product Description
Fmoc-D-Asp-Otbu is a high-quality protected amino acid derivative widely used in solid-phase peptide synthesis (SPPS). This compound features the Fmoc (9-fluorenylmethoxycarbonyl) protecting group on the alpha-amino function and a tert-butyl (OtBu) ester on the side chain carboxyl group. The D-configuration of aspartic acid makes it essential for synthesizing peptides with specific stereochemical requirements.
Researchers and chemists rely on Fmoc-D-Asp-Otbu for its stability and compatibility with standard Fmoc chemistry protocols. The tert-butyl ester protection ensures orthogonal deprotection strategies, allowing selective cleavage under acidic conditions without affecting other protecting groups. This makes it a versatile building block for complex peptide sequences.
Whether you’re working on therapeutic peptides, biochemical studies, or structural biology, this reagent delivers consistent results. The 1g pack size is ideal for small-scale synthesis and experimental work, providing enough material for multiple reactions while maintaining cost efficiency.
Need high-purity Fmoc-D-Asp-Otbu for your research? Buy online now from eqipped for guaranteed quality and fast shipping.
When handling this compound, follow standard laboratory safety protocols. Store in a cool, dry place away from moisture and incompatible substances. The product is stable under recommended storage conditions, but prolonged exposure to air or humidity may affect its performance.
FAQs
What is the purity of Fmoc-D-Asp-Otbu from Merck?
This product meets Merck’s high-quality standards, typically with purity ≥98% as determined by HPLC analysis. Exact specifications are available in the certificate of analysis provided with each batch.
How should I store Fmoc-D-Asp-Otbu?
Store the product at -20°C in a tightly sealed container. Protect from light and moisture. For long-term storage, consider using a desiccant in the container. Always allow the product to reach room temperature before opening to prevent condensation.
Can I use this for automated peptide synthesis?
Yes, Fmoc-D-Asp-Otbu is fully compatible with standard automated peptide synthesizers. Its solubility characteristics and coupling efficiency make it suitable for both manual and automated SPPS protocols.
What is the typical coupling time for this amino acid derivative?
Under standard Fmoc chemistry conditions, coupling times typically range from 30 to 60 minutes. Exact timing may vary based on your specific synthesis protocol and the sequence being assembled.
Does eqipped provide bulk quantities of Fmoc-D-Asp-Otbu?
While this listing is for the 1g pack size, eqipped can arrange larger quantities upon request. Contact our customer support team for bulk pricing and availability information.
