Description
Specifications Table
| Product Name | Fmoc-D-Glu(Otbu)-Oh |
|---|---|
| Quantity/Pack Size | 25 G |
| Form | Solid |
| Grade | Research Grade |
| Application | Peptide Synthesis |
Product Description
Fmoc-D-Glu(Otbu)-Oh is a high-quality protected amino acid derivative widely used in solid-phase peptide synthesis. This compound features the Fmoc (9-fluorenylmethoxycarbonyl) protecting group on the alpha amine and a tert-butyl ester (OtBu) on the side chain carboxyl group. These protective groups ensure stability during synthesis while allowing selective deprotection under mild conditions.
Researchers and chemists rely on Fmoc-D-Glu(Otbu)-Oh for its exceptional purity and consistency. The D-glutamic acid configuration makes it particularly useful in studies involving bacterial cell wall components, antimicrobial peptides, and other specialized applications where the D-enantiomer is required. Its compatibility with standard Fmoc chemistry protocols makes it a staple in both academic and industrial peptide synthesis workflows.
When you buy Fmoc-D-Glu(Otbu)-Oh online from eqipped, you’re getting a product that meets rigorous quality standards. Each batch undergoes strict quality control to ensure optimal performance in your experiments. Whether you’re working on drug discovery, protein engineering, or biochemical research, this reagent provides the reliability you need for reproducible results.
Need high-purity peptide synthesis reagents? Buy Fmoc-D-Glu(Otbu)-Oh 25g online today for your research needs.
The tert-butyl ester protection on the side chain carboxyl group offers excellent stability against racemization and side reactions during coupling steps. This protection can be efficiently removed using mild acid conditions, typically with trifluoroacetic acid (TFA), making it compatible with standard peptide synthesis protocols. The Fmoc group, meanwhile, can be cleaved using basic conditions like piperidine, allowing for orthogonal deprotection strategies.
For researchers working on complex peptide sequences or those requiring D-amino acids for specific biological activities, Fmoc-D-Glu(Otbu)-Oh provides an essential building block. Its use extends to various fields including medicinal chemistry, structural biology, and materials science where precise control over peptide sequences is crucial.
At eqipped, we understand the importance of reliable reagents in scientific research. That’s why we source our Fmoc-D-Glu(Otbu)-Oh from trusted manufacturers like Merck, ensuring you receive a product that meets the highest standards of quality and performance. Our streamlined ordering process makes it easy to get the supplies you need when you need them.
FAQs
What is the purity of Fmoc-D-Glu(Otbu)-Oh?
This product typically has a purity of 99% or higher, making it suitable for demanding research applications.
How should I store Fmoc-D-Glu(Otbu)-Oh?
Store at room temperature in a tightly sealed container. For extended storage, keep in a desiccator to prevent moisture absorption.
What is the molecular weight of Fmoc-D-Glu(Otbu)-Oh?
The molecular weight is approximately 425.47 g/mol, though this may vary slightly depending on the specific batch.
Can I use this for Fmoc solid-phase peptide synthesis?
Yes, this compound is specifically designed for Fmoc-based peptide synthesis protocols and is compatible with standard coupling reagents.
What is the typical yield when using Fmoc-D-Glu(Otbu)-Oh in peptide synthesis?
With proper synthesis conditions, you can expect high coupling efficiencies, typically above 95% for most standard peptide sequences.
