Specifications Table

Product Name – FMOC-D -Isoleucine

Quantity/Pack Size – 500 mg

Form – White to off-white powder

Grade – Research Grade

Application – Peptide Synthesis, Biochemical Research, Medicinal Chemistry

Product Overview

FMOC-D-Isoleucine stands as a critical building block for researchers engaged in complex peptide synthesis and advanced biochemical explorations. This high-purity protected D-amino acid is meticulously crafted to meet the stringent demands of modern laboratory applications. The Fmoc (9-fluorenylmethyloxycarbonyl) protecting group offers robust protection of the amino group, enabling mild deprotection conditions that are compatible with a wide array of functional groups present in diverse peptide sequences. This characteristic makes it particularly valuable for solid-phase peptide synthesis (SPPS), where stepwise coupling and deprotection reactions require precision and efficiency.

The D-isomer of isoleucine plays a unique role in scientific discovery, often employed in the development of peptidomimetics, drug design, and the synthesis of peptides with enhanced stability against proteolytic degradation. Its incorporation into peptide structures can lead to novel pharmacological properties and improved bioavailability, making it indispensable for pharmaceutical research. Our FMOC-D-Isoleucine is subjected to rigorous quality control measures, ensuring exceptional purity and consistency across batches. This commitment to quality guarantees reliable and reproducible experimental outcomes, empowering researchers to achieve their scientific objectives with confidence. Trust in this essential reagent for your demanding synthetic and biochemical endeavors, providing the foundation for groundbreaking discoveries and robust molecular constructs.

FMOC-D-Isoleucine is primarily used as a building block in solid-phase peptide synthesis (SPPS), biochemical research, and medicinal chemistry for creating peptides with unique structural and functional properties, often involving D-amino acids.

2. How should FMOC-D-Isoleucine be stored to maintain its integrity?

It should be stored in a cool, dry place, ideally at 2-8°C, away from direct light and moisture, in a tightly sealed container to prevent degradation and ensure its purity and stability over time.

3. Is this product suitable for creating enzyme-resistant peptides?

Yes, the incorporation of D-amino acids like D-Isoleucine can significantly enhance the resistance of peptides to proteolytic enzymes, making it highly suitable for synthesizing enzyme-resistant peptides for various research applications.

4. What is the significance of the Fmoc protecting group in this compound?

The Fmoc (9-fluorenylmethyloxycarbonyl) protecting group allows for mild deprotection conditions, typically using a weak base, which is crucial in solid-phase peptide synthesis to avoid damage to sensitive amino acid side chains and the peptide resin.

5. Can FMOC-D-Isoleucine be used in conjunction with other protected amino acids?

Absolutely. It is designed to be compatible with a wide range of other Fmoc-protected L- and D-amino acids, allowing for the construction of diverse and complex peptide sequences in a modular fashion.

FAQs

1. What is FMOC-D-Isoleucine primarily used for?