Description
Specifications Table
| Product Name | Fmoc-D-Trp-Oh |
|---|---|
| Quantity/Pack Size | 5 GM |
| Form | Powder |
| Grade | Research Grade |
| Application | Peptide Synthesis, Biochemical Research |
Product Description
What is Fmoc-D-Trp-Oh?
Fmoc-D-Trp-Oh is a protected amino acid derivative widely used in peptide synthesis. The Fmoc (9-fluorenylmethoxycarbonyl) group safeguards the amino terminus, while the D-Trp (D-tryptophan) residue ensures chiral purity. This compound is essential for researchers working on solid-phase peptide synthesis (SPPS), where precise control over amino acid sequences is critical.
Key Applications in Research
This reagent is indispensable in biochemical and pharmaceutical research. It allows scientists to incorporate tryptophan residues into peptides without racemization. Whether you’re synthesizing bioactive peptides or studying protein interactions, Fmoc-D-Trp-Oh ensures high yields and purity. Many labs rely on it for drug discovery, enzyme studies, and structural biology projects.
Why This Grade Matters
The research-grade purity of this product guarantees minimal impurities, reducing experimental errors. Merck’s stringent quality control ensures batch-to-batch consistency, so your results remain reproducible. For students and educators, this means fewer failed experiments and more reliable data.
Handling and Storage
Store Fmoc-D-Trp-Oh in a cool, dry place away from direct sunlight. Keep the container tightly sealed to prevent moisture absorption, which can degrade the compound. Always use it in a well-ventilated lab environment with proper protective equipment.
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Compatibility with Synthesis Protocols
This product integrates seamlessly with standard Fmoc-based SPPS protocols. It’s compatible with common coupling reagents like HATU, HBTU, and DIC, making it versatile for various synthesis strategies. Researchers appreciate its solubility in DMF and other organic solvents, simplifying workflows.
Safety Considerations
While Fmoc-D-Trp-Oh is generally safe when handled properly, always follow lab safety guidelines. Avoid inhalation or direct contact with skin and eyes. Dispose of waste according to local regulations to minimize environmental impact.
FAQs
What is the shelf life of Fmoc-D-Trp-Oh?
When stored correctly, this product has a shelf life of 24 months from the date of manufacture. Always check the expiration date on the label.
Can I use this for large-scale peptide synthesis?
Yes, Fmoc-D-Trp-Oh is suitable for both small and large-scale synthesis. Ensure proper scaling of reagents and solvents for optimal results.
Is this product compatible with automated peptide synthesizers?
Absolutely. Its high purity and consistent quality make it ideal for automated systems, reducing clogging and improving synthesis efficiency.
How do I verify the purity of this compound?
You can confirm purity using HPLC or mass spectrometry. Merck provides certificates of analysis with each batch for your reference.
Where can I buy Fmoc-D-Trp-Oh in India?
You can buy Fmoc-D-Trp-Oh online from eqipped, a trusted supplier of lab chemicals and reagents across India.
