Description
Specifications Table
| Product Name | Fmoc-D-Tyr(tBu)-OH |
|---|---|
| Pack Size | 5g |
| Form | Powder |
| Grade | Peptide Synthesis |
| Application | Solid-phase peptide synthesis, Fmoc chemistry |
Product Description
Fmoc-D-Tyr(tBu)-OH is a premium-grade amino acid derivative widely used in peptide synthesis. This protected tyrosine variant ensures high coupling efficiency and minimal side reactions, making it a preferred choice for researchers and pharmaceutical labs. The Fmoc (9-fluorenylmethoxycarbonyl) protecting group allows for orthogonal deprotection, while the tert-butyl (tBu) group safeguards the tyrosine hydroxyl functionality.
Whether you’re working on therapeutic peptides, diagnostic reagents, or biochemical studies, this reagent delivers consistent results. Its high solubility in organic solvents like DMF and DCM ensures smooth integration into standard Fmoc-based protocols. For labs prioritizing reproducibility and yield, Fmoc-D-Tyr(tBu)-OH is an indispensable building block.
Need reliable peptide synthesis reagents? Buy Fmoc-D-Tyr(tBu)-OH online from eqipped for guaranteed purity and fast shipping.
Key Applications
This compound is essential for synthesizing peptides containing D-tyrosine, a non-natural amino acid that enhances stability and bioactivity. Common applications include:
- Development of protease-resistant peptides
- Synthesis of peptide-based drugs and vaccines
- Research in enzymology and structural biology
Storage and Handling
Store Fmoc-D-Tyr(tBu)-OH in a cool, dry place away from direct sunlight. Keep the container tightly sealed to prevent moisture absorption. For long-term storage, refrigerate at 2–8°C. Always handle in a well-ventilated area using appropriate PPE (gloves, lab coat, safety goggles).
Safety Information
This product is for laboratory use only. Avoid inhalation, ingestion, or skin contact. In case of accidental exposure, rinse thoroughly with water and seek medical attention. Dispose of waste material in accordance with local regulations.
FAQs
What is the purity of Fmoc-D-Tyr(tBu)-OH?
This product meets Merck’s stringent quality standards, typically offering ≥98% purity as confirmed by HPLC and NMR analysis.
Can I use this for large-scale peptide synthesis?
Yes, Fmoc-D-Tyr(tBu)-OH is suitable for both small-scale research and industrial peptide production. Its high solubility and stability make it ideal for automated synthesizers.
How does the tBu protecting group benefit synthesis?
The tert-butyl group prevents unwanted side reactions at the tyrosine hydroxyl, ensuring clean coupling and deprotection steps during Fmoc-based synthesis.
Is this product compatible with microwave-assisted synthesis?
Yes, it can be used in microwave-assisted peptide synthesis, but optimize reaction conditions to avoid thermal degradation of the Fmoc group.
Where can I buy Fmoc-D-Tyr(tBu)-OH in India?
You can buy Fmoc-D-Tyr(tBu)-OH online from eqipped, a trusted supplier of high-quality lab chemicals and reagents across India.
