Description
Specifications Table
| Product Name | Fmoc-Gln(Trt)-OH |
|---|---|
| Quantity/Pack Size | 25 GM |
| Form | Powder |
| Grade | Research |
| Application | Peptide Synthesis |
Product Description
Fmoc-Gln(Trt)-OH is a premium-quality, Fmoc-protected glutamine derivative widely used in solid-phase peptide synthesis (SPPS). This compound features a trityl (Trt) side-chain protection, ensuring stability during synthesis while allowing efficient deprotection under mild acidic conditions. Researchers and students working on peptide-based projects rely on this high-purity reagent for consistent results in both manual and automated synthesis protocols.
The 25g pack size is ideal for small to medium-scale research applications, providing sufficient quantity for multiple synthesis cycles without excessive waste. Whether you’re synthesizing bioactive peptides, therapeutic candidates, or experimental compounds, Fmoc-Gln(Trt)-OH from Merck delivers the reliability needed for reproducible outcomes.
When you buy Fmoc-Gln(Trt)-OH online from eqipped, you get authentic Merck products with verified purity and documentation. Our streamlined ordering process ensures quick delivery to labs across India, so you can focus on your research without delays.
Why This Product Stands Out
This particular Fmoc-Gln(Trt)-OH variant is preferred by researchers for several reasons. The trityl protection group offers excellent stability during synthesis while being easily removable with trifluoroacetic acid (TFA), making it compatible with standard SPPS protocols. The Fmoc protection on the alpha-amino group ensures orthogonal deprotection strategies, which is crucial for complex peptide sequences.
For students learning peptide chemistry, this compound serves as an excellent teaching tool to demonstrate protection strategies and coupling efficiencies. Educators often include it in advanced organic chemistry or biochemistry lab modules to showcase modern synthesis techniques.
Applications in Research
Fmoc-Gln(Trt)-OH finds applications in various research areas, including:
- Development of therapeutic peptides for drug discovery
- Synthesis of peptide-based vaccines
- Creation of peptide probes for biochemical assays
- Preparation of peptide standards for analytical methods
- Structural biology studies involving peptide-protein interactions
Its versatility makes it a staple in both academic and industrial research settings. The 25g packaging is particularly suitable for research groups that need to maintain a steady supply without overstocking.
Handling and Storage Recommendations
To maintain the integrity of Fmoc-Gln(Trt)-OH, store it in a cool, dry place away from direct light. The compound should be kept in its original container with the lid tightly sealed to prevent moisture absorption. For long-term storage, consider using a desiccator or storing at 2-8°C.
When handling, use standard laboratory safety practices including gloves and eye protection. While this compound is generally stable under recommended conditions, it’s good practice to minimize exposure to air and humidity during use.
Quality Assurance
As a Merck product, this Fmoc-Gln(Trt)-OH batch undergoes rigorous quality control testing to ensure purity, identity, and performance. The certificate of analysis is available upon request, providing transparency about the product’s specifications. This level of quality assurance is particularly important for researchers who need consistent results across multiple experiments.
When you purchase from eqipped, you’re getting the same high-quality product that researchers worldwide trust, with the added benefit of local support and quick delivery within India.
FAQs
What is the shelf life of Fmoc-Gln(Trt)-OH?
The product typically has a shelf life of 24 months when stored properly at 2-8°C. Always check the expiration date on the package for specific batch information.
Can I use this for automated peptide synthesizers?
Yes, this Fmoc-Gln(Trt)-OH is compatible with most automated peptide synthesizers. Its solubility characteristics and protection groups make it suitable for standard SPPS protocols.
What solvents work best for dissolving Fmoc-Gln(Trt)-OH?
The compound is generally soluble in dimethylformamide (DMF) and N-methyl-2-pyrrolidone (NMP), which are commonly used in peptide synthesis. Always follow your specific synthesis protocol for optimal results.
Is this product suitable for therapeutic peptide development?
While this is a research-grade product, many researchers use it in early-stage development of therapeutic peptides. For clinical applications, additional purity testing and regulatory compliance would be required.
How does the trityl protection compare to other glutamine protection groups?
The trityl group offers excellent stability during synthesis and is easily removed with mild acid treatment, making it one of the most popular choices for glutamine protection in SPPS.
