Description
Specifications Table
| Product Name | Fmoc-Glu(Biotinyl-Peg)-Oh |
|---|---|
| Quantity/Pack Size | 5 g |
| Form | Solid |
| Grade | Research Grade |
| Application | Peptide Synthesis, Bioconjugation, Drug Discovery |
Product Description
Fmoc-Glu(Biotinyl-Peg)-Oh is a specialized peptide synthesis reagent designed for researchers and biochemists working on advanced bioconjugation and drug discovery projects. This high-purity compound features an Fmoc-protected glutamic acid linked to a biotinylated PEG spacer, making it an essential tool for creating biotin-labeled peptides and proteins.
Whether you’re developing diagnostic assays, studying protein interactions, or synthesizing therapeutic peptides, this reagent ensures reliable results with minimal side reactions. The PEG spacer enhances solubility and reduces steric hindrance, while the biotin tag enables easy detection and purification using streptavidin-based systems.
At eqipped, we understand the importance of quality in research. That’s why we source this product directly from Merck, ensuring consistent performance and batch-to-batch reliability. Our streamlined ordering process makes it easy to buy Fmoc-Glu(Biotinyl-Peg)-Oh online, with fast shipping across India so you can focus on your experiments without delay.
Upgrade your peptide synthesis workflow with premium-grade Fmoc-Glu(Biotinyl-Peg)-Oh. Order today and experience seamless bioconjugation results.
Key Applications
This versatile reagent finds applications in multiple research areas:
In peptide chemistry, it serves as a building block for introducing biotin tags into synthetic peptides. The Fmoc protection allows for standard solid-phase peptide synthesis protocols, while the PEG spacer provides flexibility in the final molecule’s structure.
For protein research, the biotin tag enables efficient purification and detection. The PEG linker helps maintain protein function by reducing interference from the biotin moiety.
In drug discovery programs, this compound helps create targeted therapeutics where biotin-mediated delivery is desired. The precise control over biotin placement ensures consistent biological activity.
Handling and Storage
To maintain product integrity, store Fmoc-Glu(Biotinyl-Peg)-Oh at -20°C in a desiccated environment. Always use proper personal protective equipment when handling, as with all fine chemicals. For best results, allow the reagent to reach room temperature before opening to prevent moisture condensation.
When working with this compound, use standard peptide synthesis solvents and follow established Fmoc deprotection protocols. The biotin-PEG moiety is stable under typical synthesis conditions but should be protected from prolonged exposure to strong acids or bases.
Why Researchers Choose This Product
Scientists across India trust this Merck product for its consistent performance in demanding applications. The combination of high purity, reliable biotinylation efficiency, and the flexibility provided by the PEG spacer makes it a preferred choice for both academic and industrial research labs.
Compared to alternative biotinylation reagents, this compound offers better water solubility and reduced non-specific binding, leading to cleaner experimental results. The Fmoc protection ensures compatibility with automated peptide synthesizers, making it suitable for high-throughput applications.
FAQs
What is the molecular weight of Fmoc-Glu(Biotinyl-Peg)-Oh?
The exact molecular weight depends on the PEG chain length, but it typically ranges between 800-1200 g/mol. For precise values, refer to the certificate of analysis provided with your order.
Can this reagent be used for in vivo applications?
While primarily designed for in vitro research, some studies have used similar biotin-PEG compounds for in vivo applications. Always conduct proper toxicity and biocompatibility testing before animal studies.
What is the typical coupling efficiency in peptide synthesis?
With proper activation and coupling conditions, you can expect >95% efficiency. Using HATU or HBTU as coupling reagents often provides the best results with this compound.
How does the PEG spacer length affect performance?
The PEG spacer in this product is
