Description
Specifications Table
| Product Name | FMOC-L-Tyr(tBu)-OH (Fmoc-O-tert-Butyl-L-tyrosine) | TC1676 | CDH |
|---|---|
| Pack Size | 5 gm – 25 gm – 100 gm – 1 kg |
| Form | Powder |
| Grade | Research Grade |
| Application | Peptide synthesis, biochemical research |
Product Description
FMOC-L-Tyr(tBu)-OH, also known as Fmoc-O-tert-Butyl-L-tyrosine, is a high-purity amino acid derivative widely used in peptide synthesis. This compound features an Fmoc (9-fluorenylmethoxycarbonyl) protecting group on the amino terminus and a tert-butyl (tBu) protecting group on the tyrosine hydroxyl side chain. These protections ensure stability during synthesis and allow for selective deprotection when needed.
Peptide chemists and researchers rely on FMOC-L-Tyr(tBu)-OH for its reliability in solid-phase peptide synthesis (SPPS). The Fmoc group is base-labile, making it compatible with standard SPPS protocols, while the tBu group protects the tyrosine side chain from unwanted reactions. This combination ensures high coupling efficiency and minimal side reactions, resulting in cleaner peptide products.
At eqipped, we source this product from trusted suppliers to guarantee consistent quality and performance. Whether you’re synthesizing therapeutic peptides, studying protein interactions, or developing new biochemical tools, this reagent provides the purity and functionality you need.
Looking for a reliable FMOC-L-Tyr(tBu)-OH supplier? Shop now for research-grade quality at competitive prices.
This product is particularly valuable for researchers working on:
- Custom peptide synthesis for drug discovery
- Protein structure-function studies
- Enzyme-substrate interaction research
- Development of peptide-based diagnostics
The tert-butyl protection on the tyrosine side chain prevents phosphorylation or other modifications during synthesis, allowing for precise control over the final peptide structure. When you’re ready to deprotect, the tBu group can be efficiently removed using mild acid conditions, while the Fmoc group is cleaved with bases like piperidine.
For laboratories and research institutions across India, eqipped offers convenient online ordering with fast shipping. Our packaging maintains product integrity during transit, and our customer support team is available to assist with any technical questions about this or other peptide synthesis reagents.
Need bulk quantities or custom packaging? Contact us for tailored solutions for your research needs.
FAQs
What is FMOC-L-Tyr(tBu)-OH used for?
It’s primarily used in solid-phase peptide synthesis as a protected tyrosine derivative. The Fmoc group protects the amino terminus, while the tBu group protects the hydroxyl side chain.
How do I deprotect FMOC-L-Tyr(tBu)-OH?
The Fmoc group is removed with 20% piperidine in DMF, while the tBu group requires mild acid treatment (typically TFA) for deprotection.
What’s the difference between FMOC-L-Tyr(tBu)-OH and regular FMOC-Tyr-OH?
The tBu version has an additional tert-butyl protection on the tyrosine hydroxyl group, preventing side reactions during synthesis that could occur with the unprotected version.
Can I use this for large-scale peptide synthesis?
Yes, this product is suitable for both small-scale research and larger production runs. For bulk requirements, contact eqipped for customized solutions.
How should I store FMOC-L-Tyr(tBu)-OH?
Store at -20°C for long-term stability, or at room temperature for short-term use (up to 3 months). Always keep the container tightly sealed.
