Description
Specifications Table
| Product Name | Fmoc-Lys(Ivdde)-Oh 1 G | 8.52082.0001 | Merck |
|---|---|
| Quantity/Pack Size | 1 G |
| Form | Solid |
| Grade | Peptide Synthesis Grade |
| Application | Solid-phase peptide synthesis, orthogonal protection strategies |
Product Description
Fmoc-Lys(Ivdde)-Oh is a specialized amino acid derivative designed for advanced peptide synthesis. The ivDde (1-(4,4-dimethyl-2,6-dioxocyclohexylidene)ethyl) protecting group offers orthogonal protection, allowing selective deprotection without affecting other functional groups. This makes it indispensable for researchers working on complex peptide sequences or post-translational modifications.
Whether you’re synthesizing therapeutic peptides or studying protein interactions, this reagent ensures high coupling efficiency and minimal side reactions. The Fmoc (9-fluorenylmethoxycarbonyl) protection is compatible with standard solid-phase synthesis protocols, while the ivDde group can be selectively removed using mild hydrazine conditions.
At eqipped, we source this product directly from Merck, guaranteeing consistent quality and batch-to-batch reliability. Each 1g pack is rigorously tested for purity, making it suitable for both academic research and industrial applications.
Key Applications
This reagent is particularly useful for:
- Synthesis of branched or cyclic peptides
- Orthogonal protection strategies in multi-step syntheses
- Preparation of peptide conjugates for drug delivery
- Research involving lysine modifications
Need bulk quantities or custom packaging? Contact eqipped’s support team for tailored solutions.
Handling and Storage
Store at -20°C in a desiccated environment. Avoid exposure to moisture or light. For best results, use within 12 months of purchase.
Safety Information
Risk Note: This product is for research use only. Not intended for human consumption. Wear appropriate PPE (gloves, goggles) when handling. Refer to the SDS for detailed safety protocols.
FAQs
What is the purity of Fmoc-Lys(Ivdde)-Oh from eqipped?
Our product meets Merck’s specifications, typically >95% purity as confirmed by HPLC. Each batch includes a certificate of analysis.
How do I remove the ivDde protecting group?
The ivDde group can be selectively cleaved using 2% hydrazine in DMF for 10-15 minutes at room temperature.
Is this product compatible with automated peptide synthesizers?
Yes, it’s designed for standard Fmoc-based solid-phase synthesis protocols used in most automated systems.
What’s the shelf life of Fmoc-Lys(Ivdde)-Oh?
When stored properly at -20°C, the product remains stable for at least 12 months from the date of manufacture.
Can I buy smaller quantities than 1g?
Currently, we offer this product in 1g packs. For custom quantities, please contact our sales team at eqipped.
