Description
Specifications Table
| Product Name | Fmoc-Tyr(tBu)-Ser(ψMe,MePro)-OH | 8.52189.0025 | Merck |
|---|---|
| Pack Size | 25 G |
| Form | Solid |
| Grade | Peptide Synthesis Grade |
| Application | Solid-Phase Peptide Synthesis (SPPS) |
Product Description
Fmoc-Tyr(tBu)-Ser(ψMe,MePro)-OH is a specialized amino acid derivative designed for high-efficiency peptide synthesis. This compound features a protected tyrosine (Tyr) with a tert-butyl (tBu) group and a serine analog with a pseudoproline (ψMe,MePro) modification. The Fmoc (9-fluorenylmethoxycarbonyl) protecting group ensures compatibility with standard solid-phase peptide synthesis (SPPS) protocols.
Researchers and peptide chemists rely on this reagent for its ability to minimize aggregation during synthesis, improving yield and purity. The pseudoproline modification enhances solubility, making it particularly useful for synthesizing difficult sequences. Whether you’re working on therapeutic peptides, biochemical studies, or custom peptide projects, this product delivers consistent performance.
At eqipped, we source this high-quality reagent directly from Merck, ensuring authenticity and batch-to-batch reliability. Our streamlined ordering process makes it easy to buy Fmoc-Tyr(tBu)-Ser(ψMe,MePro)-OH online, with fast shipping across India. Need a reliable supplier for peptide synthesis reagents? Shop now and experience hassle-free procurement.
Key Applications
This reagent is widely used in:
- Solid-phase peptide synthesis (SPPS)
- Synthesis of complex or aggregation-prone peptide sequences
- Therapeutic peptide development
- Biochemical and structural biology research
Why This Product Stands Out
Peptide synthesis can be challenging, especially with sequences prone to aggregation or secondary structure formation. Fmoc-Tyr(tBu)-Ser(ψMe,MePro)-OH addresses these issues with its unique modifications:
The pseudoproline (ψMe,MePro) group disrupts beta-sheet formation, reducing aggregation during synthesis. This leads to higher coupling efficiencies and fewer deletions or truncations in the final peptide. The tert-butyl protection on tyrosine prevents side reactions, ensuring clean deprotection during synthesis.
For researchers in India, finding a trusted supplier of such specialized reagents can be difficult. eqipped simplifies this by offering genuine Merck products with transparent pricing and quick delivery. Looking for the best Fmoc-Tyr(tBu)-Ser(ψMe,MePro)-OH price? Order online today and get your lab supplies without delays.
Handling and Storage
To maintain the integrity of this reagent, store it at -20°C in a desiccated environment. Avoid exposure to moisture, as it can lead to premature deprotection or degradation. Always use dry solvents and inert atmospheres during synthesis to prevent side reactions.
For long-term storage, keep the container tightly sealed and minimize exposure to light. When handling, use standard laboratory safety practices, including gloves and eye protection.
Risk Note
This product is for research and laboratory use only. It is not intended for human or animal consumption. Handle with care in a controlled environment, following standard chemical safety protocols. Refer to the Safety Data Sheet (SDS) for detailed hazard information.
FAQs
What is Fmoc-Tyr(tBu)-Ser(ψMe,MePro)-OH used for?
This reagent is primarily used in solid-phase peptide synthesis (SPPS) to improve the synthesis of difficult or aggregation-prone peptide sequences. The pseudoproline modification enhances solubility and reduces secondary structure formation.
How does the pseudoproline modification help in peptide synthesis?
The pseudoproline (ψMe,MePro) group disrupts beta-sheet formation, which is a common cause of aggregation during synthesis. This leads to smoother coupling reactions and higher overall yields.
What is the shelf life of this product?
When stored properly at -20°C in a desiccated environment, this product has a shelf life of at least 12 months. Always check the certificate of analysis for specific batch details.
Can I use this reagent for large-scale peptide synthesis?
Yes, this product is suitable for both small-scale and large-scale SPPS. However, for bulk requirements, it’s best to consult with eqipped for customized solutions.
Where can I buy Fmoc-Tyr(tBu)-Ser(ψMe,MePro)-OH online in India?
You can purchase this product directly from eqipped, a trusted supplier of lab reagents in India. We offer competitive pricing, fast shipping, and genuine Merck products.
