Description
Specifications Table
Product Name – Heptanesulfonic acid sodium salt monohydrate, HPLC grade
Quantity/Pack Size – 25GR, 5GR, 100GR, 500GR
Form – Solid (powder/crystals)
Grade – HPLC
Application – Ion-pair chromatography, reversed-phase HPLC
Product Overview
Heptanesulfonic acid sodium salt monohydrate is a high-purity ion-pairing reagent specifically designed for HPLC applications. This HPLC-grade compound ensures minimal UV absorbance, making it ideal for sensitive chromatographic separations where baseline stability is critical. The sodium salt form provides excellent solubility in aqueous mobile phases, enabling efficient pairing with cationic analytes to improve retention and resolution. Its monohydrate structure guarantees consistent performance across batches, eliminating variability in chromatographic results. The reagent is rigorously tested to meet strict purity standards, ensuring compatibility with modern HPLC systems and detectors. With its low impurity profile, it minimizes ghost peaks and baseline drift, allowing for accurate quantification of target compounds. The solid form (powder or crystals) offers long-term stability when stored under recommended conditions, preserving its ion-pairing efficiency. This product is particularly valued in analytical laboratories for its ability to enhance separation of polar and ionic compounds in reversed-phase chromatography without compromising column integrity.
FAQs
1. What is the primary function of sodium heptanesulfonate in HPLC?
It acts as an ion-pairing reagent that neutralizes charged analytes, improving their retention and separation on reversed-phase columns by forming neutral ion pairs that interact more effectively with the stationary phase.
2. Can this be used with gradient HPLC methods?
Yes, it is compatible with gradient elution, though concentration consistency in the mobile phase is recommended to maintain reproducible retention times throughout the gradient.
3. How does this compare to other ion-pairing reagents like TFA?
Sodium heptanesulfonate offers stronger ion-pairing for hydrophobic cations compared to TFA, which is more volatile and often used for LC-MS applications where non-volatile salts must be avoided.
4. What is the recommended storage condition for long-term stability?
Store in a tightly sealed container at room temperature (15-25°C), protected from moisture and light to prevent hydration changes or degradation of the solid form.
5. Is this suitable for LC-MS applications?
No, its non-volatile nature makes it incompatible with LC-MS as it can contaminate the ion source and suppress ionization, unlike volatile reagents like formic acid or ammonium formate.
