Description
Specifications Table
Product Name – Isopropylmagnesium chloride – Lithium chloride complex, 1.3M solution in THF, AcroSeal®
Quantity/Pack Size – 100ML, 800ML
Form – Liquid (THF solution)
Grade – AcroSeal®
Application – Organometallic synthesis, Grignard reactions
Product Overview
This isopropylmagnesium chloride-lithium chloride complex is a 1.3M solution in tetrahydrofuran (THF), specifically formulated for high-performance organometallic chemistry applications. The AcroSeal® packaging ensures maximum protection against moisture and oxygen, preserving the reagent’s reactivity and extending shelf life. The complex offers enhanced solubility and stability compared to traditional Grignard reagents, making it ideal for demanding synthetic procedures. The lithium chloride component modifies the reagent’s basicity and reactivity profile, enabling selective transformations that are difficult to achieve with conventional magnesium organometallics. The THF solvent provides excellent solvation properties while maintaining compatibility with most organic substrates. This solution is particularly valued in research settings where precise control over reaction conditions is critical. The airtight packaging system prevents solvent evaporation and contamination, ensuring consistent performance across multiple experiments. As a moisture-sensitive reagent, proper handling under inert atmosphere is recommended to maintain optimal reactivity.
FAQs
1. What is the typical shelf life of this complex when stored properly?
The solution maintains its specified concentration for at least 12 months from the date of manufacture when stored unopened at room temperature in its original AcroSeal® packaging. Once opened, it should be used within 6 months for best results.
2. Can this reagent be used with other solvents besides THF?
The complex is specifically formulated for THF, which provides optimal solvation. While it may be compatible with some ether solvents like diethyl ether, performance characteristics may differ significantly from those in THF.
3. What safety precautions should be taken when handling this solution?
As with all organometallic reagents, this solution is highly moisture-sensitive and pyrophoric. Handle under nitrogen or argon atmosphere using standard air-free techniques. Always wear appropriate PPE including gloves, goggles, and lab coat.
4. How does the lithium chloride affect the reagent’s properties?
The lithium chloride component enhances the reagent’s solubility in THF and modifies its basicity, often leading to improved selectivity in nucleophilic addition reactions compared to traditional Grignard reagents.
5. What is the recommended storage temperature for this complex?
The solution should be stored at room temperature (15-25°C) in a dry, well-ventilated area away from ignition sources and incompatible materials. Avoid refrigeration as this may cause solvent separation.
