Description
Specifications Table
| Product Name | Lichrospher 100 Diol (5 µm) 10 G | 1.16152.0010 | Merck |
|---|---|
| Quantity/Pack Size | 10 GM |
| Form | Silica gel (DIOL-modified) |
| Grade | HPLC |
| Application | Normal phase HPLC, chiral separations, polar compound analysis |
Product Description
When precision and reproducibility matter in your HPLC workflows, the Lichrospher 100 Diol (5 µm) from Merck stands out as a trusted choice for researchers and analyticians. This high-purity DIOL-modified silica gel is engineered for normal phase chromatography, offering exceptional selectivity for polar compounds, isomers, and chiral molecules. Whether you’re working in academic labs, pharmaceutical R&D, or quality control environments, this stationary phase delivers the performance you need to achieve sharp, well-resolved peaks.
With a particle size of 5 µm, this DIOL HPLC stationary phase ensures efficient separations with minimal backpressure, making it ideal for both analytical and semi-preparative applications. The diol functionalization provides a hydrophilic surface that enhances retention for polar analytes, a critical advantage when traditional C18 or silica columns fall short. This makes it a go-to option for method development in complex matrices like natural extracts, synthetic intermediates, or enantiomeric mixtures.
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FAQs
What is Lichrospher 100 Diol (5 µm) used for in HPLC?
Lichrospher 100 Diol (5 µm) is a DIOL-modified silica gel designed for normal phase HPLC. It is particularly effective for separating polar compounds, enantiomers, and isomers that may not be well-retained on reversed-phase columns. Its diol functionalization provides a hydrophilic surface that enhances selectivity for polar analytes.
How does Lichrospher 100 Diol differ from standard silica columns?
While standard silica columns rely on a bare silica surface for separations, Lichrospher 100 Diol features a diol-bonded phase that offers a more polar and stable surface. This modification reduces tailing for basic compounds and provides better retention for polar analytes, making it a more versatile option for normal phase applications.
Can I use Lichrospher 100 Diol for reversed-phase HPLC?
No, Lichrospher 100 Diol is specifically designed for normal phase HPLC. For reversed-phase applications, you would need a stationary phase like C18 or C8. The diol phase is not compatible with the aqueous mobile phases typically used in reversed-phase HPLC.
What mobile phases are compatible with Lichrospher 100 Diol?
Lichrospher 100 Diol works best with non-polar solvents like hexane, heptane, or dichloromethane, often modified with polar solvents such as isopropanol, ethanol, or methanol. The choice of mobile phase depends on the polarity of your analytes and the desired retention times.
Where can I buy Lichrospher 100 Diol (5 µm) in India?
You can buy Lichrospher 100 Diol (5 µm) online at eqipped, a trusted supplier of high-quality lab consumables and chemicals in India. eqipped offers authentic Merck products with fast delivery and competitive pricing, ensuring you get the best materials for your research or academic needs.
