Description
Specifications Table
Product Name – Lithium aluminium hydride, 2.4M solution in THF, AcroSeal®
Quantity/Pack Size – 100ML, 800ML
Form – Solution
Grade – Reagent
Application – Reducing agent, organic synthesis
Product Overview
Lithium aluminium hydride (LiAlH₄) as a 2.4M solution in tetrahydrofuran (THF) is a powerful reducing agent widely used in organic synthesis for converting esters, carboxylic acids, and ketones into their corresponding alcohols. The AcroSeal® packaging ensures minimal exposure to moisture, preserving the reagent’s reactivity and extending shelf life. This solution is stabilized in THF, a polar aprotic solvent that enhances solubility and reaction efficiency. The reagent is highly reactive with water and alcohols, necessitating careful handling under inert conditions. Its high purity and consistent concentration make it suitable for demanding laboratory applications where precise stoichiometry is critical. The solution is typically stored under nitrogen or argon to prevent degradation. Due to its strong reducing properties, it is incompatible with oxidizing agents and should be handled with appropriate protective equipment. The reagent’s versatility extends to both small-scale and bulk synthesis, making it a staple in research and development settings.
FAQs
1.
What precautions should be taken when handling this solution?
Always use this solution in a fume hood with proper ventilation. Wear moisture-resistant gloves, safety goggles, and a lab coat. Avoid contact with water or alcohols, as it reacts violently. 2.
Is this solution compatible with glassware?
Yes, but ensure the glassware is thoroughly dried and free of moisture. Use oven-dried or flame-dried glassware to prevent accidental reactions. 3.
Can this be used for large-scale reductions?
The 800ML pack size is suitable for moderate-scale reactions, but for industrial applications, bulk quantities may be required. Always assess reaction exothermicity. 4.
How should this solution be stored?
Store under an inert atmosphere (nitrogen/argon) in a cool, dry place. Keep the container tightly sealed and away from ignition sources. 5.
What alternatives exist for less moisture-sensitive reductions?
Sodium borohydride (NaBH₄) is a milder alternative, though less potent. For specific substrates, consider DIBAL-H or catalytic hydrogenation.
