Description
Specifications Table
Product Name – Lithium tert-butoxide, 2.2M solution in THF, AcroSeal® Quantity/Pack Size – 100ML, 800ML Form – Liquid (solution in THF) Grade – AcroSeal® (moisture-sensitive) Application – Strong base for organic synthesis
Product Overview
Lithium tert-butoxide, 2.2M solution in THF, is a highly reactive strong base widely used in organic synthesis for deprotonation and condensation reactions. The AcroSeal® packaging ensures minimal exposure to moisture, preserving the reagent’s potency and extending shelf life. This solution offers superior solubility in THF, making it ideal for homogeneous reactions where precise control over basicity is required. The 2.2M concentration provides a balance between reactivity and ease of handling, reducing the need for dilution while maintaining high efficiency. As a non-nucleophilic base, it selectively deprotonates acidic substrates without competing side reactions, ensuring cleaner product formation. The sealed packaging prevents contamination, making it suitable for air-sensitive applications. Whether used in small-scale research or larger syntheses, this reagent delivers consistent performance with minimal batch-to-batch variation.
FAQs
1. What is the shelf life of lithium tert-butoxide 2.2M in THF?
The sealed AcroSeal® packaging ensures stability for up to 24 months when stored under recommended conditions.
2. Can this solution be used with other solvents besides THF?
While optimized for THF, it can be diluted with anhydrous solvents like diethyl ether or toluene, but compatibility should be verified.
3. How should this reagent be stored to maintain purity?
Store in a cool, dry place under inert gas (argon/nitrogen) and keep the container tightly sealed to prevent moisture absorption.
4. Is this product compatible with glassware?
Yes, but ensure glassware is dry and free of residual moisture to avoid decomposition or reduced reactivity.
5. What alternatives exist for similar applications?
Sodium tert-butoxide or potassium tert-butoxide can be used, but lithium offers milder basicity and better solubility in THF.
