Description
Specifications Table
Product Name – Lithium (trimethylsilyl)acetylide, 0.5M solution in THF, AcroSeal®
Quantity/Pack Size – 100ML, 800ML
Form – Solution (0.5M in THF)
Grade – Synthesis Grade
Application – Organic synthesis, nucleophilic addition, alkyne formation
Product Overview
Lithium (trimethylsilyl)acetylide is a highly reactive organolithium reagent supplied as a 0.5M solution in tetrahydrofuran (THF) for consistent performance in synthetic applications. The trimethylsilyl group enhances stability while maintaining reactivity, making it ideal for nucleophilic addition and alkyne formation reactions. Packaged in AcroSeal® bottles, this solution ensures minimal exposure to air and moisture, preserving its potency and extending shelf life. The synthesis-grade purity guarantees reliable results in laboratory settings, with the THF solvent providing compatibility with a wide range of organic reactions. This reagent is particularly valued for its ability to introduce alkyne functionalities under controlled conditions, offering chemists a versatile tool for complex molecular constructions. The sealed packaging eliminates the need for additional inert gas handling, simplifying workflow while maintaining high standards of chemical integrity.
FAQs
1.
What is the shelf life of lithium (trimethylsilyl)acetylide in THF?
The shelf life is typically 12 months from the date of manufacture when stored unopened in its original AcroSeal® packaging at recommended conditions. 2.
Is this reagent compatible with glassware?
Yes, it is compatible with standard laboratory glassware, but ensure all equipment is dry and free from moisture before use. 3.
Can this solution be used for large-scale synthesis?
While primarily designed for laboratory-scale applications, the 800ML pack size accommodates larger reaction volumes with proper handling. 4.
What precautions should be taken during storage?
Store at 2-8°C, away from moisture and air. Keep the container tightly sealed when not in use to prevent degradation. 5.
Are there alternatives for moisture-sensitive applications?
For extremely moisture-sensitive reactions, consider using freshly prepared solutions or alternative silyl-protected acetylides with higher stability profiles.
