Description
Specifications Table
Product Name – Methylmagnesium iodide, 3M solution in diethyl ether, AcroSeal®
Quantity/Pack Size – 100ML, 800ML
Form – Liquid (solution in diethyl ether)
Grade – Reagent
Application – Grignard reagent for organic synthesis
Product Overview
Methylmagnesium iodide (3M in diethyl ether) is a highly reactive Grignard reagent supplied in AcroSeal® packaging to prevent moisture contamination and ensure long-term stability. This reagent-grade solution is standardized at 3 molar concentration, offering consistent performance in carbon-carbon bond formation, nucleophilic addition, and other organometallic reactions. The diethyl ether solvent enhances solubility while maintaining the reagent’s reactivity, making it ideal for laboratory-scale syntheses requiring precise stoichiometry. The AcroSeal® technology provides an airtight, resealable container that minimizes exposure to atmospheric moisture, extending shelf life and reducing waste. Compatible with standard Schlenk techniques, this solution eliminates the need for in-house preparation, saving time and resources. Its high purity and controlled concentration ensure reproducible results in research and development applications where methyl group transfer is critical.
FAQs
1.
What is the typical shelf life of this methylmagnesium iodide solution?
The AcroSeal® packaging maintains stability for up to 12 months when stored unopened at recommended temperatures, though reactivity may gradually decrease after opening. 2.
Can this reagent be used directly without titration?
While the 3M concentration is standardized, best practice involves titration before critical reactions due to potential solvent evaporation or minor degradation over time. 3.
Is this solution compatible with THF as a co-solvent?
Yes, the diethyl ether solution can be diluted with anhydrous THF, though concentration adjustments may be needed for reaction optimization. 4.
What precautions are needed for handling this reagent?
Handle under inert atmosphere (N₂/Ar) using dry syringes or cannula techniques; avoid exposure to air or protic solvents to prevent violent decomposition. 5.
Are there lower-concentration alternatives available for less reactive substrates?
Lower molarities (e.g., 1M or 1.5M) are typically prepared by dilution, but pre-diluted commercial options may be sourced separately for specific applications.
