Description
Specifications Table
Product Name – N-alpha-(2,4-Dinitro-5-fluorophenyl)-L-alaninamide, 98%
Quantity/Pack Size – 100MG
Form – Solid powder
Grade – 98% (HPLC)
Application – Peptide synthesis, fluorinated amino acid derivative studies, biochemical labeling
Product Overview
N-alpha-(2,4-Dinitro-5-fluorophenyl)-L-alaninamide is a high-purity (98%) fluorinated dinitrophenyl derivative of L-alanine designed for specialized biochemical applications requiring precise molecular modifications. The compound’s unique structure combines a fluorinated aromatic ring with a dinitro substitution pattern, creating a reactive moiety that maintains stability under standard laboratory conditions while enabling selective conjugation reactions. The alanine backbone provides chiral specificity, making it particularly valuable for stereoselective synthesis protocols. This reagent undergoes rigorous quality control to ensure batch-to-batch consistency in purity (verified via HPLC at ≥98%) and molecular integrity. The solid powder form offers convenient handling and accurate weighing for micro-scale applications. Its distinct UV-visible absorption profile (characteristic of dinitrophenyl groups) enables straightforward reaction monitoring via spectrophotometric methods. The fluorinated component introduces additional analytical possibilities through 19F NMR spectroscopy, providing an extra dimension for structural confirmation in complex synthesis pathways. Storage under desiccated conditions at 2-8°C preserves the compound’s reactivity profile for extended periods, with minimal degradation observed even after prolonged storage when proper handling protocols are followed.
FAQs
1. What is the exact molecular weight of this DNF-alanine amide derivative?
The molecular weight is 312.23 g/mol, calculated from its chemical formula C9H9FN4O5.
2. Can this compound be used for Fmoc-based peptide synthesis?
While structurally compatible, the dinitrophenyl protecting group requires specific deprotection conditions different from standard Fmoc chemistry.
3. What solvents provide optimal solubility for this reagent?
It shows good solubility in DMSO, DMF, and acetone, with limited solubility in water or alcohols.
4. How does the fluorine substitution affect the compound’s reactivity?
The fluorine atom increases electrophilicity of the aromatic ring while maintaining the dinitrophenyl group’s characteristic reactivity patterns.
5. What analytical techniques work best for purity verification?
HPLC with UV detection at 340-360nm provides reliable purity assessment, complemented by 19F NMR for fluorine confirmation.
