Description
Specifications Table
| Product Name | N-Biotinyl-Nh-(Peg)2-Cooh Middot Dipea ( | 8.51029.0001 | Merck) |
|---|---|
| Quantity/Pack Size | 1 G |
| Form | Solid |
| Grade | Research Grade |
| Application | Bioconjugation, Drug Delivery, Diagnostic Assays |
Product Description
N-Biotinyl-Nh-(Peg)2-Cooh Middot Dipea is a specialized biotinylated PEG linker designed for precise bioconjugation applications. This high-purity compound, sourced from Merck, features a PEG2 spacer that enhances solubility and reduces steric hindrance in biomolecular interactions. Researchers and biochemists rely on this biotin PEG2 COOH for labeling proteins, nucleic acids, and other biomolecules, making it indispensable in drug delivery systems, diagnostic assays, and targeted therapies.
The inclusion of Dipea (N,N-Diisopropylethylamine) ensures optimal reactivity during synthesis, while the biotin moiety provides strong affinity for avidin/streptavidin systems. Whether you’re developing biosensors, affinity purification protocols, or cellular imaging tools, this biotin PEG carboxylic acid delivers consistent performance. At eqipped, we prioritize quality and authenticity, offering this product in a 1G pack size to meet diverse research needs.
Upgrade your bioconjugation workflow with this premium biotin PEG2 COOH. Order now for seamless integration into your experiments.
Key Applications
This biotinylated PEG linker excels in:
- Protein and antibody labeling for immunoassays
- Surface functionalization in biosensors
- Drug-targeting strategies via PEGylation
- Affinity chromatography and purification
- Fluorescent or radioactive probe conjugation
Why This Product Stands Out
Unlike generic biotin linkers, this compound’s PEG2 spacer offers a balanced hydrophilic profile, improving conjugation efficiency without compromising target binding. The carboxylic acid terminus allows for straightforward coupling via EDC/NHS chemistry, while the biotin group ensures high-affinity binding to streptavidin-coated surfaces. For researchers seeking reproducibility and minimal batch-to-batch variability, this Merck-sourced product is a trusted choice.
Storage and Handling
Store at -20°C in a desiccated environment to maintain stability. Avoid repeated freeze-thaw cycles. For long-term storage, aliquot under inert gas. Always use in a fume hood with appropriate PPE, as Dipea is a volatile base.
FAQs
What is the shelf life of N-Biotinyl-Nh-(Peg)2-Cooh Middot Dipea?
When stored as recommended, the product remains stable for 24 months from the date of manufacture. Check the certificate of analysis for batch-specific details.
Can this biotin PEG2 COOH be used for in vivo studies?
While primarily designed for in vitro applications, it can be adapted for preclinical studies with proper validation. Consult literature for PEGylation stability in biological systems.
How does the PEG2 spacer improve conjugation efficiency?
The short PEG2 chain reduces steric hindrance near the biotin group, allowing better accessibility for streptavidin binding while maintaining water solubility.
Is this product compatible with click chemistry?
No, this compound lacks azide or alkyne groups. For click chemistry applications, consider biotin PEG linkers with terminal alkynes or azides.
Where can I buy biotin PEG2 COOH in India?
eqipped offers authentic Merck-sourced N-Biotinyl-Nh-(Peg)2-Cooh Middot Dipea with fast shipping across India. Order online for research-grade quality.
