Description
Specifications Table
Product Name – n-Butyllithium, 1.6M in hexane
Quantity/Pack Size – 100ML
Form – Liquid (solution in hexane)
Grade – Laboratory Grade
Application – Organic synthesis, polymerization, deprotonation
Product Overview
n-Butyllithium (n-BuLi) is a highly reactive organolithium compound supplied as a 1.6M solution in hexane, offering exceptional purity and stability for demanding laboratory applications. This reagent is widely recognized for its strong basicity and nucleophilicity, making it indispensable in organic synthesis for initiating anionic polymerization, deprotonating weak acids, and facilitating carbon-carbon bond formation. The hexane solvent ensures optimal solubility and reactivity while maintaining controlled handling conditions. Designed for precision, this solution is free from impurities that could interfere with sensitive reactions, ensuring reproducible results in research and development settings. Its standardized concentration (1.6M) simplifies dosage calculations, reducing experimental variability. The product is packaged in airtight, moisture-resistant containers to prevent degradation from atmospheric exposure, with a shelf life optimized for long-term storage under inert conditions. Ideal for chemists requiring a reliable, high-performance lithiation agent, this n-Butyllithium solution adheres to strict quality control measures, guaranteeing consistency across batches for critical applications.
FAQs
1. What is the typical shelf life of n-Butyllithium 1.6M in hexane under proper storage?
The shelf life is approximately 12 months when stored at 2–8°C under an inert atmosphere, away from moisture and air. Always check the manufacturer’s expiry date on the label for precise guidance.
2. Can this solution be used directly for lithiation reactions without further dilution?
Yes, the 1.6M concentration is suitable for most lithiation reactions without dilution. However, for reactions requiring lower concentrations, it can be diluted with anhydrous hexane or other compatible solvents under inert conditions.
3. What precautions should be taken when handling n-Butyllithium in hexane?
Handle under a dry nitrogen or argon atmosphere using air-free techniques. Wear flame-resistant lab coats, gloves, and goggles, as the solution is pyrophoric and reacts violently with water or air. Use in a well-ventilated fume hood.
4. Is this product compatible with glassware, or are specific materials recommended?
The solution is compatible with borosilicate glassware, but avoid using plastic or rubber components, as they may react with the reagent. PTFE-coated or stainless-steel syringes are recommended for transfers.
5. How does the hexane solvent affect the reactivity of n-Butyllithium?
Hexane acts as an inert solvent that stabilizes the reagent while maintaining its reactivity. It does not participate in side reactions, ensuring the n-BuLi remains effective for targeted lithiation or polymerization processes.
