Description
Specifications Table
| Product Name | N-Methyl-N-Trimethylsilyl-Trifluoroacetamide |
|---|---|
| Pack Size | 2 mL |
| Form | Liquid |
| Grade | For GC derivatization |
| Application | Silylation reagent for GC-MS, metabolomics, and forensic analysis |
Product Description
N-Methyl-N-Trimethylsilyl-Trifluoroacetamide (MSTFA) is a highly reactive silylation reagent widely used in gas chromatography-mass spectrometry (GC-MS) for derivatizing polar compounds. This Merck-certified reagent ensures reliable and reproducible results, making it a staple in research labs, forensic analysis, and metabolomics studies.
MSTFA reacts rapidly with active hydrogen groups (e.g., alcohols, amines, and carboxylic acids) to form stable trimethylsilyl (TMS) derivatives, enhancing volatility and thermal stability for GC-MS analysis. Its low boiling point and high purity minimize background interference, ensuring clean chromatograms.
Whether you’re analyzing metabolites, drugs, or environmental samples, MSTFA from eqipped delivers consistent performance. Need a dependable derivatization reagent for your GC-MS workflow? Shop now for lab-grade MSTFA.
Key Applications
MSTFA is essential for:
- Metabolomics research (e.g., fatty acids, steroids, sugars)
- Forensic toxicology (drug screening, pesticide analysis)
- Environmental testing (pollutant identification)
- Pharmaceutical development (impurity profiling)
Why MSTFA?
Unlike other silylation reagents, MSTFA offers:
- Faster reaction times (often complete in minutes)
- Minimal side reactions (cleaner derivatives)
- Compatibility with automated sample preparation
For researchers seeking precision, eqipped provides Merck’s MSTFA in a convenient 2 mL pack size—ideal for high-throughput labs.
Safety and Handling
MSTFA is a moisture-sensitive reagent. Store under inert gas (e.g., nitrogen) at 2–8°C. Avoid skin contact and use in a fume hood. Refer to the SDS for full safety guidelines.
FAQs
What is MSTFA used for in GC-MS?
MSTFA is a silylation reagent that converts polar compounds into volatile TMS derivatives, improving their detection in GC-MS.
How do I use MSTFA for derivatization?
Typically, mix 50–100 µL of MSTFA with your sample, heat at 60–80°C for 15–30 minutes, and inject into the GC-MS.
Is MSTFA compatible with all GC-MS columns?
Yes, but avoid prolonged exposure to high temperatures to prevent column degradation.
Can I buy MSTFA in bulk?
eqipped offers MSTFA in 2 mL packs. For larger quantities, contact our support team.
What’s the shelf life of MSTFA?
When stored properly (sealed, under nitrogen), MSTFA remains stable for 12–24 months.
