Description
Specifications Table
| Product Name | Na-FMOC-N(im)-Trityl-L-Histidine (FMOC-His(Trt)-OH) extrapure, 99% |
|---|---|
| Pack Size | 10 Gms, 100 Gms |
| Form | Powder |
| Grade | Extrapure |
| Application | Peptide synthesis, biochemical research |
Product Description
When precision matters in peptide synthesis, FMOC-His(Trt)-OH stands out as a trusted choice for researchers and lab professionals. This extrapure-grade histidine derivative, with 99% purity, ensures minimal impurities and consistent performance in your experiments. Whether you’re working on complex peptide chains or biochemical assays, this protected amino acid offers the reliability you need.
At eqipped, we understand the importance of high-quality lab supplies. That’s why we source this product from reputable manufacturers to meet the strict standards of academic and industrial research. The trityl protection group on the imidazole ring prevents side reactions, making it ideal for solid-phase peptide synthesis (SPPS).
Looking for a reliable FMOC histidine supplier? Order now for guaranteed purity and fast shipping across India.
The FMOC (fluorenylmethyloxycarbonyl) protection on the alpha-amino group allows for orthogonal deprotection strategies, giving you greater control over your synthesis workflow. This makes it particularly valuable for synthesizing histidine-rich peptides or proteins where side-chain protection is critical.
For students and educators, this product serves as an excellent teaching tool for demonstrating amino acid protection strategies in organic chemistry labs. Its high purity ensures reproducible results, making it a staple in both research and educational settings.
Why This Product Stands Out
Unlike generic histidine derivatives, this extrapure version undergoes rigorous quality checks to ensure batch-to-batch consistency. The 99% purity specification means you can trust your experimental outcomes without worrying about contaminant interference. This level of quality is especially important when working with sensitive assays or when synthesizing peptides for therapeutic applications.
Many researchers prefer FMOC-His(Trt)-OH for its stability during storage and handling. The trityl group provides excellent protection against oxidation and other degradation pathways, extending the shelf life of your reagent. This stability translates to fewer failed experiments and more reliable data.
Applications in Research
This product finds extensive use in:
- Solid-phase peptide synthesis (SPPS)
- Histidine-containing peptide synthesis
- Biochemical assays requiring protected amino acids
- Protein engineering and modification studies
- Educational demonstrations of amino acid protection chemistry
In peptide synthesis, the choice of protecting groups can make or break your experiment. The combination of FMOC on the alpha-amino group and trityl on the imidazole ring offers a balanced approach to protection and deprotection, allowing for clean synthesis of complex peptides.
Handling and Storage
To maintain the integrity of your FMOC-His(Trt)-OH, store it in a cool, dry place away from direct sunlight. Keep the container tightly sealed when not in use to prevent moisture absorption. For long-term storage, consider using a desiccator to maintain optimal conditions.
When handling, use standard laboratory safety practices including gloves and eye protection. While this product is generally stable under normal conditions, always work in a well-ventilated area or fume hood when performing chemical manipulations.
Quality Assurance
Every batch of this product undergoes comprehensive quality control testing to verify purity and identity. The extrapure designation means it meets stringent specifications for use in demanding applications. When you buy from eqipped, you’re getting a product that has been carefully selected for its performance and reliability.
Need high-purity FMOC histidine for your next synthesis? Shop now and experience the eqipped difference in quality and service.
Technical Support
Our team of lab supply specialists is available to answer your questions about this product or its applications. Whether you need guidance on proper handling, storage conditions, or compatibility with your specific synthesis protocol, we’re here to help you achieve successful results.
FAQs
What is the difference between FMOC-His(Trt)-OH and regular histidine?
FMOC-His(Trt)-OH is a protected derivative of histidine used in peptide synthesis. The FMOC group protects the alpha-amino group, while the trityl group protects the imidazole ring, preventing unwanted side reactions during synthesis.
Can I use this product for therapeutic peptide synthesis?
Yes, the high purity (99%) and extrapure grade make it suitable for synthesizing peptides intended for therapeutic applications, though additional purification may be required depending on your specific needs.
What’s the typical shelf life of FMOC-His(Trt)-OH?
When stored properly in a cool, dry place with the container tightly sealed, this product typically maintains its specifications for 12-24 months from the date of manufacture.
Is this product suitable for educational lab demonstrations?
Absolutely. The clear protection strategy and reliable performance make it an excellent choice for teaching amino acid chemistry and peptide synthesis techniques in academic settings.
How does the trityl protection benefit peptide synthesis?
The trityl group on the imidazole ring prevents side reactions and oxidation during synthesis, allowing for cleaner reactions and higher yields of the desired peptide product.
Risk Note
While generally stable, this chemical should be handled with standard laboratory precautions. Avoid inhalation and direct contact with skin or eyes. Use appropriate personal protective equipment and work in a well-ventilated area or fume hood.
