Description
Specifications Table
Product Name – N,N’-Dicyclohexylcarbodiimide, 1M solution in dichloromethane, AcroSeal®
Quantity/Pack Size – 100ML
Form – Liquid solution
Grade – Reagent grade
Application – Coupling reagent, peptide synthesis, esterification
Product Overview
N,N’-Dicyclohexylcarbodiimide (DCC) is a highly efficient coupling reagent supplied as a 1M solution in dichloromethane (DCM) under the AcroSeal® brand, ensuring optimal purity and stability. This reagent is widely recognized for its role in facilitating amide bond formation, making it indispensable in organic synthesis, particularly in peptide synthesis and esterification reactions. The solution is prepared in anhydrous DCM, which enhances solubility and reactivity while minimizing side reactions. The AcroSeal® packaging guarantees protection against moisture and atmospheric contamination, preserving the reagent’s integrity for consistent performance. With a reagent-grade purity, this DCC solution is ideal for applications requiring high yields and minimal byproduct formation. Its stability in solution form eliminates the need for weighing, reducing handling risks and improving workflow efficiency in laboratory settings.
FAQs
1. What is the shelf life of N,N’-Dicyclohexylcarbodiimide 1M solution in DCM?
The shelf life is typically 12-24 months when stored unopened at room temperature in a dry, well-ventilated area away from direct sunlight.
2. Is this DCC solution compatible with other organic solvents?
While formulated in DCM, it can be used with other anhydrous solvents like THF or DMF, but compatibility should be verified based on specific reaction conditions.
3. Are there alternatives to DCC for coupling reactions?
Alternatives include EDC (1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide) and DIC (Diisopropylcarbodiimide), which may offer different solubility or reactivity profiles.
4. How should this solution be stored to maintain stability?
Store tightly sealed in the original AcroSeal® container under inert gas if possible, at 2-8°C for long-term storage, and avoid exposure to moisture.
5. What is the typical reaction time when using this DCC solution?
Reaction times vary by application, but most coupling reactions complete within 2-24 hours under standard conditions.
