Description
Specifications Table
Product Name – N,N-Dimethylacetamide, 99.8+%, for HPLC
Quantity/Pack Size – 1LT, 2.5LT
Form – Liquid
Grade – HPLC
Application – Chromatography, solvent extraction, synthesis
Product Overview
N,N-Dimethylacetamide (DMAc) is a high-purity, polar aprotic solvent with a minimum assay of 99.8%, specifically formulated for high-performance liquid chromatography (HPLC) applications. Its exceptional purity ensures minimal interference in analytical procedures, making it ideal for sensitive chromatographic separations. The solvent exhibits low UV absorbance, which is critical for accurate detection in UV-Vis spectroscopy and HPLC systems. Its high polarity and miscibility with water and organic solvents enhance its versatility in various laboratory processes, including synthesis, extraction, and purification. DMAc is also valued for its stability under a wide range of temperatures and conditions, reducing the risk of degradation during prolonged storage or use. The absence of residual impurities, such as water, acids, or aldehydes, guarantees consistent performance in demanding applications. This grade is particularly suited for researchers and analysts requiring reliable, reproducible results in their chromatographic workflows.
FAQs
1. What is the shelf life of HPLC-grade N,N-Dimethylacetamide?
When stored in a tightly sealed container under cool, dry conditions, away from direct sunlight and moisture, HPLC-grade N,N-Dimethylacetamide typically retains its specified purity for up to 24 months from the date of manufacture. Always check the label for the exact expiration date.
2. Is this solvent compatible with standard HPLC columns?
Yes, this grade of N,N-Dimethylacetamide is fully compatible with most reverse-phase and normal-phase HPLC columns, including C18, silica, and cyano phases. Its low UV cutoff and high purity minimize column degradation and baseline noise.
3. Can this be used as a substitute for dimethylformamide (DMF) in reactions?
While N,N-Dimethylacetamide shares similar solvent properties with DMF, such as high polarity and aprotic nature, it may not always be a direct substitute due to differences in boiling point, viscosity, and reactivity. Always verify compatibility with your specific reaction conditions.
4. How should this solvent be stored to maintain its purity?
Store the solvent in its original airtight container, preferably under an inert atmosphere if opened frequently. Keep it in a well-ventilated, cool area (below 25°C) and avoid exposure to humidity or oxidative agents to prevent contamination.
5. Does this product contain any stabilizers or additives?
No, this HPLC-grade N,N-Dimethylacetamide is free from added stabilizers, preservatives, or other additives, ensuring maximum purity for analytical applications. The 99.8%+ assay is achieved through rigorous distillation and purification processes.










