Description
Specifications Table
Product Name – N,N-Dimethylacetamide GC
Quantity/Pack Size – 1 L
Form – Liquid
Grade – GC (Gas Chromatography)
Application – Chromatography, analytical testing, solvent extraction
Product Overview
N,N-Dimethylacetamide (DMAc) GC is a high-purity, polar aprotic solvent specifically formulated for gas chromatography and advanced analytical applications. Its low volatility and excellent solvency power make it a preferred choice for dissolving a wide range of polar and non-polar compounds, ensuring accurate separation and detection in chromatographic analysis. The GC-grade purity minimizes interference, providing consistent and reproducible results even in trace-level determinations. This solvent is also valued for its thermal stability, which prevents degradation during high-temperature chromatographic runs. Its miscibility with water and organic solvents further enhances its versatility in multi-solvent systems. Whether used as a mobile phase modifier or a sample diluent, N,N-Dimethylacetamide GC delivers exceptional performance in demanding laboratory environments. The solvent undergoes rigorous quality control to meet strict chromatographic standards, ensuring batch-to-batch reliability. Its hygroscopic nature necessitates proper storage to maintain purity, making it essential for laboratories prioritizing precision and reproducibility in their analytical workflows.
FAQs
1. What is the shelf life of N,N-Dimethylacetamide GC when stored under ideal conditions?
When stored in a tightly sealed container at room temperature, away from moisture and direct sunlight, N,N-Dimethylacetamide GC typically retains its specified purity for up to 24 months from the date of manufacture. Always check the certificate of analysis for exact expiration details.
2. Can this solvent be used as a substitute for dimethylformamide (DMF) in chromatographic applications?
While N,N-Dimethylacetamide shares similar solvent properties with DMF, its slightly higher boiling point and different selectivity may affect separation profiles. It can replace DMF in some applications, but method validation is recommended to ensure comparable performance.
3. What precautions should be taken when handling N,N-Dimethylacetamide GC due to its hygroscopic nature?
Always use the solvent in a dry environment and minimize exposure to air. Transfer the required quantity quickly, reseal the container immediately, and consider using a desiccant in the storage area to prevent moisture absorption, which could alter its chromatographic properties.
4. Is this grade of N,N-Dimethylacetamide compatible with HPLC systems, or is it strictly for GC?
The GC grade is optimized for gas chromatography, but its high purity also makes it suitable for certain HPLC applications, particularly when low UV absorbance and minimal impurity interference are critical. However, HPLC-grade solvents are generally preferred for liquid chromatography to avoid potential column contamination.
5. How does the polarity of N,N-Dimethylacetamide GC compare to other common chromatographic solvents like acetonitrile?
N,N-Dimethylacetamide is more polar than acetonitrile, with a higher dipole moment and stronger hydrogen-bond accepting ability. This increased polarity can enhance the solvation of polar analytes but may also lead to longer retention times in reverse-phase chromatography compared to less polar solvents.










