Description
Specifications Table
Product Name – N,N-Dimethylacetamide USP
Quantity/Pack Size – 100 ml
Form – Liquid
Grade – USP
Application – Solvent for organic synthesis, pharmaceutical formulations
Product Overview
N,N-Dimethylacetamide (DMAc) USP is a high-purity polar aprotic solvent widely recognized for its versatility in laboratory and industrial applications. This colorless to pale yellow liquid boasts a high boiling point (166°C) and excellent solvency power, making it suitable for dissolving a broad range of organic and inorganic compounds. Its USP-grade certification ensures minimal impurities, including water content below 0.1%, which is critical for sensitive reactions and formulations. The solvent exhibits low volatility, reducing evaporation losses during prolonged use, and its miscibility with water and most organic solvents enhances its utility in multi-component systems. DMAc is particularly valued for its ability to dissolve polar and non-polar substances alike, including polymers like polyvinyl chloride (PVC) and polyacrylonitrile, as well as cellulose derivatives. Its thermal stability and resistance to hydrolysis under normal conditions further contribute to its reliability in demanding laboratory environments. The solvent’s moderate viscosity (0.92 mPa·s at 25°C) allows for easy handling and precise dispensing, while its hygroscopic nature necessitates proper storage to maintain purity. Whether used as a reaction medium, extraction solvent, or processing aid, this USP-grade DMAc delivers consistent performance, ensuring reproducibility in experimental and production settings. The absence of corrosive additives or stabilizers makes it compatible with a wide array of lab equipment, including glassware and stainless steel containers.
FAQs
1. What is the typical shelf life of N,N-Dimethylacetamide USP when stored properly?
The shelf life is approximately 24 months from the date of manufacture when stored in a tightly sealed container at room temperature, away from moisture and direct sunlight. Regularly check for signs of contamination or moisture absorption before use.
2. Can this solvent be used with standard laboratory glassware, or are there compatibility concerns?
N,N-Dimethylacetamide USP is compatible with borosilicate glass and most common laboratory glassware. However, prolonged exposure to certain plastics or rubber seals may cause swelling or degradation, so it’s advisable to use PTFE-lined caps or glass stoppers for long-term storage.
3. How does the USP grade differ from technical or reagent grades of DMAc?
USP-grade DMAc undergoes stricter purification processes to meet pharmacopeial standards, ensuring lower levels of impurities such as water, heavy metals, and residual solvents. This makes it suitable for applications requiring high purity, such as pharmaceutical formulations or sensitive analytical procedures.
4. What precautions should be taken when handling N,N-Dimethylacetamide USP?
Always handle DMAc in a well-ventilated fume hood, as it can release vapors that may cause respiratory irritation. Wear appropriate personal protective equipment (PPE), including nitrile gloves, safety goggles, and a lab coat, to avoid skin and eye contact. Avoid inhaling vapors and ensure proper disposal according to local regulations.
5. Is this solvent miscible with water, and how does moisture affect its performance?
N,N-Dimethylacetamide is fully miscible with water, but its hygroscopic nature means it can absorb moisture from the air over time. Excessive moisture can alter its solvency properties and introduce impurities, so it’s critical to store it in airtight containers with desiccants if long-term stability is required.
