Specifications Table
Product Name – N,N’-DICYCLOHEXYLCARBODIIMIDE 99% For Synthesis
Quantity/Pack Size – 100 g, 500 g
Form – Crystalline Powder
Grade – Synthesis Grade (99% Purity)
Application – Peptide synthesis, esterification, and organic coupling reactions
Product Overview
N,N’-DICYCLOHEXYLCARBODIIMIDE (DCC) is a high-purity (99%) coupling reagent widely used in organic synthesis for facilitating peptide bond formation, esterification, and amide synthesis. This white crystalline powder is highly moisture-sensitive, requiring careful handling and storage under inert conditions to maintain stability. DCC acts as a dehydrating agent, promoting the formation of peptide bonds by activating carboxyl groups, making it indispensable in biochemical and pharmaceutical research. Its high reactivity ensures efficient coupling with minimal side reactions, provided optimal conditions are maintained. The synthesis-grade purity guarantees reliable results in demanding applications, while its compatibility with common organic solvents enhances versatility. Store in a cool, dry place, sealed tightly to prevent hydrolysis. Ideal for researchers requiring consistent, high-yield reactions in organic chemistry workflows.
FAQs
1
What is the primary use of DCC in organic synthesis?
DCC is primarily used as a coupling reagent to form peptide bonds between amino acids or activate carboxyl groups for esterification and amide synthesis. 2
Is DCC compatible with aqueous solvents?
No, DCC is moisture-sensitive and decomposes in water. It should be used in anhydrous organic solvents like dichloromethane or DMF. 3
What are the storage requirements for DCC?
Store DCC in a tightly sealed container under inert gas (e.g., nitrogen) in a cool, dry place to prevent moisture absorption and degradation. 4
Can DCC be substituted with other coupling reagents?
Alternatives like EDC (1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide) or DIC (Diisopropylcarbodiimide) can be used, but reaction conditions may need adjustment. 5
What safety precautions should be taken while handling DCC?
Wear gloves, goggles, and work in a fume hood. Avoid inhalation or skin contact, as DCC is an irritant and may cause allergic reactions.