Description
Specifications Table
Product Name – Phenylmagnesium bromide, 1.6M solution in CPME, AcroSeal®
Quantity/Pack Size – 100ML, 800ML
Form – Liquid (solution in CPME)
Grade – Laboratory grade
Application – Grignard reagent for organic synthesis
Product Overview
Phenylmagnesium bromide, 1.6M solution in cyclopentyl methyl ether (CPME), is a highly reactive Grignard reagent designed for precision in organic synthesis. The AcroSeal® packaging ensures airtight protection, minimizing moisture exposure and preserving reagent integrity. This solution offers a stable, ready-to-use format for nucleophilic addition, coupling, and carbon-carbon bond formation reactions. The CPME solvent enhances solubility and reactivity while reducing side reactions compared to traditional ethers. Ideal for researchers requiring consistent performance, this reagent maintains its potency under controlled storage conditions. The 1.6M concentration provides an optimal balance between reactivity and ease of handling, making it suitable for both small-scale and bulk applications. Compatibility with standard laboratory glassware and inert atmospheres further simplifies workflow integration.
FAQs
1. What is the shelf life of Phenylmagnesium bromide in CPME?
When stored under nitrogen at 2-8°C in the original AcroSeal® packaging, the solution remains stable for up to 12 months from the date of manufacture.
2. Can this reagent be used with THF as a co-solvent?
Yes, but pre-drying the THF is recommended to avoid quenching the Grignard reagent. CPME alone is often sufficient for most applications.
3. How should I dispose of excess solution?
Neutralize with isopropanol or dilute acetic acid under a fume hood, then follow local regulations for hazardous waste disposal.
4. What alternatives exist for moisture-sensitive reactions?
Phenylmagnesium chloride or lithium reagents may be considered, though reactivity profiles differ. CPME-based solutions generally offer better stability.
5. Is this compatible with Schlenk line techniques?
Yes, the AcroSeal® bottle can be adapted for cannula transfer under inert gas conditions.
