Description
Specifications Table
Product Name – Phosphorus tribromide, 1.0M solution in dichloromethane, AcroSeal®
Quantity/Pack Size – 100ML, 800ML
Form – Liquid (solution in DCM)
Grade – AcroSeal® (high-purity, moisture-sensitive)
Application – Bromination reagent, organic synthesis
Product Overview
Phosphorus tribromide (PBr₃) in a 1.0M dichloromethane (DCM) solution is a highly reactive brominating agent used extensively in organic synthesis. The AcroSeal® packaging ensures minimal exposure to moisture, preserving the reagent’s purity and reactivity. This solution is particularly valued for its ability to convert alcohols to alkyl bromides efficiently, making it indispensable in synthetic chemistry workflows. The DCM solvent enhances solubility and ease of handling, while the sealed packaging prevents degradation from atmospheric moisture. Ideal for laboratories requiring consistent performance, this solution maintains stability under standard storage conditions. Its high purity minimizes side reactions, ensuring reliable results in critical applications. The 1.0M concentration provides a balanced reactivity profile, suitable for both small-scale and larger preparative reactions. Compatibility with common lab glassware and standard synthetic protocols further enhances its utility in diverse experimental setups.
FAQs
1. What is the shelf life of phosphorus tribromide 1.0M in DCM?
When stored unopened in its original AcroSeal® packaging at room temperature, the solution remains stable for up to 24 months. Exposure to moisture or air accelerates degradation, so reseal tightly after use.
2. Can this solution be used for bromination of primary and secondary alcohols?
Yes, phosphorus tribromide in DCM is effective for converting both primary and secondary alcohols to their corresponding alkyl bromides. Reaction conditions may vary based on substrate reactivity.
3. Is this reagent compatible with standard borosilicate glassware?
The solution is compatible with most lab-grade borosilicate glassware. However, prolonged contact with moisture-sensitive reagents may require dry, inert conditions to prevent hydrolysis.
4. Are there safer alternatives to phosphorus tribromide for bromination?
Alternatives like hydrogen bromide (HBr) or tetrabutylammonium tribromide (TBATB) can be used, but they may offer different reactivity profiles. PBr₃ remains preferred for its efficiency in converting alcohols to bromides.
5. How should this solution be disposed of after use?
Neutralize excess reagent with a mild base (e.g., sodium bicarbonate solution) before disposal. Follow local hazardous waste regulations, as phosphorus tribromide and DCM are classified as hazardous materials.
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