Description
Specifications Table
Product Name – Polyethylene glycol 400
Quantity/Pack Size – 250g, 1000g
Form – Viscous liquid
Grade – Laboratory grade
Application – Solvent, stabilizer, and viscosity modifier in biochemical assays
Product Overview
Polyethylene glycol 400 (PEG 400) is a water-soluble, non-toxic polymer widely recognized for its versatility in laboratory applications. This clear, colorless, and odorless liquid exhibits low volatility and high hygroscopicity, making it an excellent solvent and stabilizer in various formulations. Its molecular weight of approximately 400 Da ensures optimal balance between viscosity and solubility, allowing seamless integration into aqueous and organic systems. PEG 400 is chemically inert, non-irritating, and biocompatible, which enhances its suitability for sensitive biochemical processes. The compound remains stable under standard lab conditions, resisting degradation from heat or light exposure. Its ability to dissolve both polar and non-polar substances makes it indispensable for creating homogeneous mixtures in research settings. Additionally, PEG 400 serves as a plasticizer in polymer synthesis and a humectant in pharmaceutical preparations, further expanding its utility. The laboratory-grade purity ensures minimal impurities, guaranteeing consistent performance in critical applications. Whether used as a cryoprotectant, a medium for drug delivery studies, or a component in electrophoresis buffers, PEG 400 delivers reliable results with precision.
FAQs
1. What is the shelf life of polyethylene glycol 400 when stored properly?
When stored in a tightly sealed container at room temperature, away from moisture and direct sunlight, polyethylene glycol 400 typically retains its stability for up to 24 months. Regular checks for contamination or changes in viscosity are recommended for long-term storage.
2. Can polyethylene glycol 400 be mixed with ethanol or other organic solvents?
Yes, polyethylene glycol 400 is miscible with ethanol, acetone, dichloromethane, and other common organic solvents. However, compatibility should be verified for specific concentrations, as high solvent ratios may alter viscosity or precipitation behavior.
3. Is polyethylene glycol 400 suitable for use in cell culture applications?
While PEG 400 is generally non-toxic, its use in cell culture depends on the specific cell line and concentration. Lower concentrations (typically <5%) are often employed as cryoprotectants or fusion agents, but cytotoxicity tests are advised prior to application.
4. How does polyethylene glycol 400 differ from higher molecular weight PEGs like PEG 4000?
PEG 400 has a lower molecular weight, resulting in higher solubility in water and organic solvents, along with lower viscosity compared to PEG 4000. Higher molecular weight PEGs form more viscous solutions and are often used in solid formulations, while PEG 400 excels in liquid applications.
5. What precautions should be taken when handling polyethylene glycol 400?
Though PEG 400 is non-hazardous, standard lab safety practices should be followed. Wear gloves and safety goggles to avoid skin or eye contact, and ensure adequate ventilation when handling large quantities to prevent inhalation of vapors during heating.
