Description
Specifications Table
| Product Name | Polyethylene Glycol 400 For Synthesis | 8.07485.2521 | Merck |
|---|---|
| Quantity/Pack Size | 2.5 LTR |
| Form | Liquid |
| Grade | For Synthesis |
| Application | Solvent, reagent, molecular biology, pharmaceuticals |
Product Description
Polyethylene Glycol 400 (PEG 400) is a high-purity, water-soluble polymer widely used in laboratories for synthesis, solvent applications, and as a reagent in molecular biology. This Merck-grade PEG 400 is ideal for researchers, students, and educators who require consistent performance in experiments. Whether you’re working on drug formulation, protein crystallization, or chemical reactions, this 2.5 LTR pack ensures you have enough for multiple applications.
PEG 400 is known for its low toxicity, high stability, and compatibility with a wide range of organic and inorganic compounds. It serves as an excellent solvent for hydrophobic substances and is often used in PCR, DNA extraction, and other biochemical assays. The synthesis-grade purity makes it suitable for sensitive applications where impurities can affect results.
When you buy polyethylene glycol 400 online from eqipped, you get a product that meets stringent quality standards. Our supply chain ensures that you receive authentic Merck chemicals with proper documentation, so you can focus on your research without worrying about consistency.
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Key Applications of Polyethylene Glycol 400
PEG 400 is a versatile compound with applications across various scientific disciplines. Here’s how it can be used in your lab:
1. Molecular Biology
PEG 400 is commonly used in DNA and RNA extraction protocols. It helps precipitate nucleic acids by reducing their solubility in aqueous solutions. Researchers also use it in PCR to stabilize enzymes and improve reaction efficiency.
2. Pharmaceutical Formulations
In drug development, PEG 400 acts as a solvent, plasticizer, and vehicle for active pharmaceutical ingredients. Its ability to enhance drug solubility makes it valuable in oral and topical formulations.
3. Chemical Synthesis
As a synthesis-grade reagent, PEG 400 is used in organic synthesis, particularly in reactions requiring a polar aprotic solvent. It’s also employed in phase-transfer catalysis and as a medium for conducting reactions at high temperatures.
4. Protein Crystallization
PEG 400 is a standard precipitant in protein crystallization screens. Its ability to induce protein aggregation under controlled conditions helps in growing high-quality crystals for X-ray crystallography.
5. Histology and Microscopy
In tissue processing, PEG 400 is used as a clearing agent to make samples transparent for better microscopic examination. It’s also used in embedding media for electron microscopy.
With such a wide range of uses, having a reliable polyethylene glycol 400 supplier is essential. eqipped ensures you get the right product for your specific needs.
Why PEG 400 is Preferred in Labs
Not all polyethylene glycol variants are the same. PEG 400 stands out due to its unique properties:
High Solubility
PEG 400 is miscible with water and many organic solvents, making it a versatile choice for diverse applications. Whether you need to dissolve hydrophobic compounds or create homogeneous mixtures, PEG 400 delivers.
Low Toxicity
Compared to other solvents, PEG 400 has minimal toxicity, making it safer for lab use. This is particularly important in pharmaceutical and biochemical applications where residue can be a concern.
Thermal Stability
PEG 400 remains stable across a wide temperature range, which is crucial for reactions requiring heating or cooling. It doesn’t degrade easily, ensuring consistent performance in your experiments.
Non-Volatile Nature
Unlike ethanol or acetone, PEG 400 doesn’t evaporate quickly. This makes it ideal for applications where you need a stable solvent that won’t alter the reaction conditions over time.
If you’re looking to buy polyethylene glycol 400 online, ensure you choose a trusted polyethylene glycol 400 supplier like eqipped to guarantee quality and authenticity.
Safety and Handling Guidelines
While PEG 400 is generally safe, proper handling ensures the best results and minimizes risks:
Storage
Store the 2.5 LTR bottle in a cool, dry place away from direct sunlight. Keep the container tightly sealed to prevent contamination or moisture absorption.
Handling
Use standard lab safety gear, including gloves and goggles, when handling PEG 400. Although it’s low in toxicity, avoiding skin and eye contact is good practice.
Disposal
Dispose of PEG 400 according to local laboratory waste regulations. Since it’s biodegradable, it can often be disposed of as non-hazardous waste, but always check with your institution’s guidelines.
Risk Note
PEG 400 is not classified as a hazardous chemical under GHS. However, ingestion or inhalation should be avoided. In case of accidental exposure, rinse with plenty of water and seek medical advice if irritation persists.
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FAQs
What is the shelf life of Polyethylene Glycol 400?
When stored properly in its original container, PEG 400 has a shelf life of 2-3 years. Always check the expiration date on the label before use.
Can PEG 400 be used in cell culture applications?
Yes, PEG 400 is often used in cell culture media as a fusion agent or to induce cell differentiation. However, ensure it’s sterile before adding it to cultures.
Is this PEG 400 suitable for HPLC applications?
While PEG 400 is not typically used as a mobile phase in HPLC, it can be used in sample preparation. For HPLC-grade solvents, consider specialized products.
How does PEG 400 differ from other PEG grades like PEG 300 or PEG 600?
The number in PEG indicates its average molecular weight. PEG 400 has a molecular weight of around 400 g/mol, making it more viscous than PEG 300 but less so than PEG 600. This affects its solubility and application suitability.
Can I buy polyethylene glycol 400 in smaller quantities?
Currently, eqipped offers PEG 400 in a 2.5 LTR pack. For smaller quantities, you may need to check with local suppliers or consider splitting the pack with colleagues.
