Description
Specifications Table
Product Name – Potassium tert-butoxide, pure, 1.6-1.7M (20 wt.%) solution in THF, AcroSeal®
Quantity/Pack Size – 100ML, 800ML
Form – Solution
Grade – Pure
Application – Strong base for organic synthesis, deprotonation reactions
Product Overview
Potassium tert-butoxide (KOtBu) in THF is a highly reactive, non-nucleophilic strong base widely used in organic synthesis. This 1.6-1.7M (20 wt.%) solution is stabilized in anhydrous tetrahydrofuran (THF) and packaged under nitrogen in AcroSeal® bottles to prevent moisture contamination. The solution maintains consistent potency due to its sealed packaging, ensuring reliable performance in deprotonation reactions, aldol condensations, and other base-catalyzed transformations. The THF solvent enhances solubility while maintaining the base’s reactivity, making it ideal for sensitive applications where precise stoichiometry is critical. The pure grade guarantees minimal impurities, reducing side reactions and improving yield. AcroSeal® packaging provides an additional layer of protection against atmospheric exposure, extending shelf life and preserving reagent integrity. This formulation is particularly valuable in air-sensitive procedures, offering convenience and safety for laboratory use.
FAQs
1. Is this potassium tert-butoxide solution compatible with glassware?
The THF solution is safe for standard borosilicate glassware, but prolonged exposure may etch soda-lime glass. Use PTFE-lined or glass-stoppered containers for storage.
2. What precautions should be taken during handling?
Handle under inert atmosphere (nitrogen/argon) due to extreme moisture sensitivity. Wear chemical-resistant gloves and safety goggles to prevent skin/eye contact.
3. Can this be used as a substitute for sodium hydride?
Yes, it offers similar basicity but with better solubility in organic solvents. However, reaction conditions may need adjustment due to differing counterions.
4. How should unused solution be stored?
Keep tightly sealed in original AcroSeal® packaging at 2-8°C, away from moisture and oxidizing agents. Avoid temperature fluctuations.
5. What’s the typical shelf life under proper storage?
Unopened bottles retain full potency for 12-18 months. Once opened, use within 3 months or re-seal under inert gas for extended stability.
