Description
Specifications Table
| Product Name | Sodium bis(2-methoxyethoxy)aluminium hydride, 70 wt% solution in toluene (ca. 3.5M), AcroSeal® |
|---|---|
| Pack Size | 100ML, 800ML |
| Form | Liquid |
| Grade | AcroSeal® |
| Application | Selective reductions in organic synthesis, research applications |
Product Description
Sodium bis(2-methoxyethoxy)aluminium hydride, commonly known as Red-Al®, is a powerful reducing agent widely used in organic synthesis. This 70% solution in toluene (approximately 3.5M) offers a balanced reactivity profile, making it suitable for selective reductions of aldehydes, ketones, carboxylic acids, and esters. The AcroSeal® packaging ensures minimal exposure to moisture and air, preserving the reagent’s potency and extending shelf life.
Researchers and chemists often prefer this reagent for its ability to reduce functional groups without affecting other sensitive moieties in the molecule. Its solubility in toluene allows for easy handling and precise dosing in laboratory settings. Whether you’re working on pharmaceutical intermediates, fine chemicals, or academic research, this high-purity solution delivers consistent results.
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The 3.5M concentration provides an optimal balance between reactivity and ease of use. Unlike other aluminum hydrides, this solution is less pyrophoric, reducing handling risks while maintaining high reducing power. It’s particularly useful in stereoselective reductions, where control over reaction conditions is critical.
For best results, store the solution under an inert atmosphere and use standard laboratory safety protocols. The AcroSeal® packaging minimizes the risk of contamination, ensuring you get the most out of every drop. Whether you’re scaling up a reaction or conducting small-scale experiments, this reagent adapts to your needs.
FAQs
What is the shelf life of sodium bis(2-methoxyethoxy)aluminium hydride solution?
When stored properly under an inert atmosphere, the solution remains stable for up to 2 years. The AcroSeal® packaging helps extend shelf life by minimizing exposure to moisture and air.
Can this reagent reduce nitriles or amides?
While it primarily targets carbonyl groups, it can reduce nitriles to amines under controlled conditions. Amides may require more forcing conditions or alternative reagents.
Is this solution compatible with aqueous workups?
No, this reagent reacts violently with water. Always quench reactions carefully with alcohols or other suitable quenching agents before aqueous workup.
What are the alternatives to sodium bis(2-methoxyethoxy)aluminium hydride?
Alternatives include lithium aluminum hydride (LiAlH₄) for stronger reductions or sodium borohydride (NaBH₄) for milder conditions. The choice depends on the specific functional groups and selectivity required.
How should I dispose of unused solution?
Follow local hazardous waste disposal regulations. Neutralize the reagent with a suitable quenching agent before disposal to prevent reactions with other waste materials.
