Description
Specifications Table
| Product Name | Sodium cyanoborohydride, 1M solution in THF, AcroSeal® |
|---|---|
| Pack Size | 100ML | 800ML |
| Form | Liquid |
| Grade | AcroSeal® |
| Application | Reductive amination, bioconjugation, organic synthesis |
Product Description
Sodium cyanoborohydride is a versatile reducing agent widely used in organic synthesis, particularly for reductive amination reactions. This 1M solution in THF (tetrahydrofuran) offers a stable and convenient format for laboratory applications. The AcroSeal® packaging ensures minimal exposure to moisture and contaminants, preserving reagent integrity.
Researchers and chemists rely on sodium cyanoborohydride for its selective reduction properties, making it ideal for bioconjugation, peptide synthesis, and carbohydrate chemistry. Whether you’re working in academia or industry, this high-purity solution delivers consistent results.
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Applications
This reagent is commonly used in:
- Reductive amination of aldehydes and ketones
- Bioconjugation of proteins and peptides
- Synthesis of pharmaceutical intermediates
- Carbohydrate modification
Safety and Handling
Risk Note: Sodium cyanoborohydride is toxic and should be handled with care. Use in a fume hood with proper PPE (gloves, goggles, lab coat). Avoid inhalation and skin contact. Dispose of waste according to local regulations.
Store the solution in a cool, dry place away from incompatible substances like strong acids or oxidizing agents. The AcroSeal® bottle provides an additional layer of protection against degradation.
Why This Product Stands Out
The 1M concentration in THF eliminates the need for weighing solid sodium cyanoborohydride, saving time and reducing handling risks. Thermofisher’s AcroSeal® technology ensures the solution remains stable until use, minimizing waste and improving reproducibility in your experiments.
For researchers who demand precision, this product offers batch-to-batch consistency, making it a trusted choice in labs across India. Whether you’re synthesizing novel compounds or modifying biomolecules, this reagent delivers reliable performance.
FAQs
What is sodium cyanoborohydride used for?
It’s primarily used for reductive amination, where it selectively reduces imines to amines without affecting other functional groups like carboxylic acids or amides.
How should I store this solution?
Keep the bottle tightly sealed at room temperature. The AcroSeal® packaging helps prevent moisture absorption, but always store it in a desiccator if possible.
Can I use this for peptide synthesis?
Yes, sodium cyanoborohydride is commonly used in peptide conjugation reactions, especially when linking peptides to carriers or labels.
Is this product compatible with aqueous solutions?
While the solution is in THF, it can be used in mixed solvent systems. However, avoid excessive water as it may decompose the reagent.
What safety precautions are necessary?
Always work in a fume hood, wear nitrile gloves, and use a lab coat. In case of spills, neutralize with dilute acid and clean immediately.