Description
Specifications Table
Product Name – Sodium methoxide, 0.5M solution in methanol, AcroSeal®
Quantity/Pack Size – 100ML, 800ML
Form – Liquid solution
Grade – AcroSeal® (high-purity, moisture-controlled)
Application – Base catalyst in transesterification, organic synthesis
Product Overview
Sodium methoxide, 0.5M solution in methanol (AcroSeal®), is a highly reactive alkaline reagent designed for demanding laboratory applications where moisture sensitivity and purity are critical. This solution combines sodium methoxide’s strong basicity with methanol’s solvating properties, creating an optimal environment for base-catalyzed reactions such as transesterification, condensation, and nucleophilic substitutions. The AcroSeal® packaging ensures minimal exposure to atmospheric moisture, preserving the reagent’s integrity and extending shelf life. With a precisely standardized 0.5M concentration, this solution eliminates the need for dilution, reducing preparation time and human error in sensitive protocols. The methanol solvent enhances solubility for organic substrates while maintaining compatibility with common glassware and reaction setups. Its clear, colorless appearance allows easy visual confirmation of purity, and the sealed packaging prevents contamination during storage. Ideal for applications requiring consistent catalytic activity, this reagent delivers reproducible results in synthetic chemistry, pharmaceutical intermediates, and specialty chemical production. The controlled formulation minimizes side reactions, improving yield and selectivity in complex multi-step syntheses.
FAQs
1. What is the shelf life of sodium methoxide 0.5M in methanol when unopened?
The AcroSeal® packaging provides a 24-month shelf life from the date of manufacture when stored unopened at room temperature in a dry environment. The moisture-barrier design significantly reduces degradation compared to standard packaging.
2. Can this solution be used directly in reactions without further purification?
Yes, the 0.5M sodium methoxide in methanol is supplied as a ready-to-use solution with high purity. The AcroSeal® technology ensures minimal moisture contamination, eliminating the need for additional drying steps in most applications.
3. What materials are incompatible with this sodium methoxide solution?
Avoid contact with strong acids, oxidizing agents, and moisture-sensitive materials. The solution will react violently with water, releasing methanol vapors. Use only in glass or PTFE-lined containers; avoid aluminum or other reactive metals.
4. How should I dispose of unused sodium methoxide solution?
Neutralize with a dilute acid (e.g., 1M HCl) in a well-ventilated fume hood before disposal. Follow local hazardous waste regulations, as the solution contains flammable methanol and corrosive sodium methoxide residues.
5. What alternatives exist if I need a different concentration?
For higher concentrations, solid sodium methoxide (95%+ purity) can be dissolved in anhydrous methanol to prepare custom solutions. Lower concentrations can be achieved by dilution with anhydrous methanol, though this may introduce moisture if not handled properly.










